Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16546 Azd-6482 GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 16 TFAP2C; CUX1; KDM5B; FOXO3; ZNF721; ERBB2; ID2; CHD8; TRIP6; SOX10; TWIST1; HOXA5; RBPJ; NR2F6; TRIB3; BASP1
Down-regulation 42 JUNB; TAF7; NR2F1; KAT6B; REPIN1; SATB2; TOB1; CCDC59; HEY1; FOXA1; JAK2; TOX; ASCL1; ARID4B; SSX1; CBFA2T3; BACH1; BHLHE41; IRF4; CUX2; HDAC9; LMCD1; NFE2L3; ZNF467; ZNF302; ZNF32; ID4; MYB; HHEX; MYRF; SMARCA1; EGR3; MNDA; SCAND1; TBX3; MXI1; NR1D2; STAT1; ZSCAN18; ZBTB18; TOX3; IKZF1