Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16543 Tgx-221 GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 319 NR3C1; E2F2; ZNF586; PPARD; RBBP7; ZNF552; ZNF587; ZNF580; GATA4; NCOA6; ARID4A; IRF4; UBP1; MZF1; ZMYND11; ZNF528; NR4A2; HCFC1; MYBBP1A; NR2F1; SETD2; SHOX; PPARGC1A; FOXC2; KMT2D; SETD3; KLF12; ADNP; DDX54; RERE; CREM; TRIM16; ELK3; WNT4; POLR2A; ESRRB; ZNF444; PHOX2B; TCF20; SP1; RBL1; ELF4; POU4F1; PIAS3; NKX2-8; MAFK; FOXH1; ZHX3; ZNF211; NR1H2; PHOX2A; HEYL; EGR1; BARX2; AFF1; HOXC13; ZNF816; POU2F2; TFEC; MBD1; TOX; ZNF768; ZNF419; ZNF304; TBL1X; PAX2; SNW1; PRDM5; RCOR1; CTNNB1; PRDM16; EZH1; GON4L; ALX4; TRRAP; ZNF446; ZSCAN2; CNOT1; IL16; TUB; NSD1; WDHD1; ZNF83; ZNF132; BATF; PEX2; FOXL2; BAZ1B; PRDM13; GATA3; ZNF324B; UBE2B; ARID3B; BAZ2A; EGR2; FOXN3; ZNF175; TCF12; PPARG; ZNF665; RFX2; KDM5A; ZNF343; NRF1; AFF4; RARA; E2F3; CDK9; HOXC8; SMAD7; ZSCAN5A; NPAS2; ELK1; HSF2; CAPN15; LIMD1; WHSC1L1; TRIM28; EBF2; E2F1; ZNF549; POU3F3; NEUROG2; HSBP1; ZNF134; FHL5; TBL1XR1; NR4A1; ZNF701; ZNF688; TLX3; EVX1; HLTF; NFIX; SIRT7; HR; NR1I3; TFE3; HOXD3; HNF1B; NR3C2; MED23; RARB; BRDT; ZNF516; SOX1; ERBB4; HIPK2; CTR9; AIRE; DDX5; PRKDC; ZBTB39; MYT1; BCL10; EPAS1; MED1; KDM5B; FOS; MXD4; MED14; KMT2A; KAT7; NFIC; ZBED1; HMGN3; ZNF35; TRIM32; ARID3A; ZNF358; SNAI1; MLLT1; ASCL1; RNF14; ZNF550; CEBPA; SNIP1; ERCC2; CDK2; TSC22D4; FOXA2; HABP4; HNF4G; CSDC2; HMGB3; FOSL2; FOXJ1; GATAD2A; ZNF415; BRF2; MNAT1; CHD3; GFI1; MED12; HOXA11; ZEB2; KLF15; SOX21; SUPT6H; KDM5C; PRRX2; LMCD1; ZNF331; HOXC10; PAX1; ZNF506; THRA; SMARCD2; BCLAF1; MXD1; UIMC1; ZNF276; CIITA; EMX2; SP2; OVOL1; ESRRG; ZNF671; ZNF551; SMAD3; DLX4; CEBPE; HOXC4; DNAJC1; TULP2; EN2; PBX1; CAMTA2; ZNF778; SMARCA2; ZNF329; BCOR; VGLL4; CBX4; NFKB1; NFKBIB; RFX5; CBX5; RNF141; ARID1A; CHD4; TBP; SMAD6; BCL3; EYA2; TLE4; HOXC6; SOX17; BRD2; CNOT3; TAL1; VDR; TULP4; ZNF835; CENPB; SSBP3; SSX1; ZNF75D; NRBF2; ANKRD1; TOB1; ID4; FLI1; CIR1; SOX13; PGR; TGIF1; BHLHE41; TCF4; TAF10; KMT5A; KLF13; ZSCAN18; LIN28A; FOSB; FOXE1; ZNF629; TRAK1; JAK2; NFATC3; TCF21; ELF3; E2F8; ZNF45; SMAD2; NKX2-1; NFE2L2; LPIN2; TRIM24; IRX5; ATF5; DACH1; MAZ; ZNF226; CREG1; USF2; MAF; HLF; STAT4; SCAND1; SATB2; FOXC1; TRIM22; EGR3; ZNF394; TBX2; ID3; NCOA1; STAT1; PEG3; HES1; KLF2; HMG20B; MECOM; MYB; HOXD1; ZNF264; TBX3; TRIB3
Down-regulation 169 HDAC3; TAF9; YBX3; PUF60; HMBOX1; ATF1; MED27; CBX3; YAP1; HOXB13; BATF3; HIRA; MAX; CEBPB; NFIB; RYBP; ZNF12; GABPB1; ATF3; SP110; MED17; RNF138; ZIC1; ZNF165; PURA; PTTG1; HTATIP2; ZZZ3; CITED2; TEAD4; CSDE1; PMS1; BTF3; ZBED2; CREB1; PFDN5; KLF4; HHEX; ZBTB11; IKBKAP; OSR2; DEK; CNBP; CREB5; ZHX2; TAF1A; KLF7; PCGF1; KLF6; TSC22D1; ASXL1; CERS6; LITAF; SP140L; ENY2; RORA; PQBP1; ZNF573; PAXBP1; ZNF500; CCNC; HDAC9; KLF11; TAF5L; NCOA4; THAP4; HMGA2; ZNF562; ADRB2; SOX9; PSPC1; GCFC2; UBTF; ZNF131; RFC1; CUX2; BCL11A; BRIP1; ZNF410; NFE2; DLX2; JUN; ZBTB1; NFIL3; APEX1; ZNF7; HOXA5; TOX3; CENPF; BBX; BTG1; ZNF74; PRPF6; TRIM29; TCEA2; SMARCD3; TCF7L2; SUB1; ZNF84; IRF1; HOXB2; ZNF146; GLI3; MED13; SMAD1; SAP18; ZNF91; NPM1; TRIM27; SUPT3H; CD3D; NKX3-1; ZNF232; TLE1; SIX2; RLF; GTF3A; MYCN; PNRC1; ZNF281; CRY1; ZNF263; SHOX2; STAT3; ZFP36L2; ARID4B; ZFHX4; USP21; SSBP2; MKL2; BRD4; RBPJ; CARHSP1; IRF8; ZNF43; ZNF593; NR2F2; HOXD11; ST18; CEBPD; ZNF3; ZBTB16; CDK8; SNAI2; ARID5B; HOXB7; SAP30; MEIS2; MTDH; TULP3; TRIP6; FOXG1; ZFP36L1; TXNIP; SATB1; ZEB1; SOX11; PAX6; WT1; ZNF184; HOXB6; ZKSCAN1; VPS72; ZNF136; TFDP2; MSX1; ID2; BASP1; ZNF430