Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16541 Tgx-221 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 72 TCEA1; BHLHE40; SREBF1; AIP; PQBP1; DACH1; ID2; PCGF3; FUBP1; IKZF1; EMX2; CITED2; WNT4; IL16; CREB3L1; MXD4; TBL1X; SMARCE1; TRIM29; MEOX2; ZBTB38; SMAD1; NHLH2; KDM5D; MEIS1; NR1H2; EYA2; RUNX3; ZNF711; AES; TRIM22; KLF13; GATA6; NCOA3; RBPMS; HOXB7; MYCL; BASP1; SOX9; MYT1L; KLF4; ZNF83; TP63; PAX6; MBD2; TLE4; SSBP3; APEX1; TOB1; PA2G4; TOX; CRYM; ZFPM2; SATB1; TXNIP; SPEN; ERBB4; HOXB2; HOXB6; HMGB1; INSM1; SMARCB1; TRIP6; IRF8; ESR1; PAX5; HOXB5; TCF4; VPS72; PEG3; TRIB3; NR2F6
Down-regulation 48 YAP1; MED17; TSC22D1; PITX2; NKX2-1; HMGA1; ZKSCAN5; BRIP1; ZNF587; NFKBIA; AGO2; PDLIM1; TTF2; ZNF274; E2F8; ZBTB16; NCOR2; ZNF12; SMAD7; HSBP1; ZNF165; ZMIZ2; MED1; ERG; BIRC2; CEBPA; SMAD6; ARID4B; JUP; FOXO3; EGR3; MKL2; ASCL1; NPAT; LMCD1; ZSCAN18; VDR; TOX3; ZNF267; ZNF551; ZNF200; KLF9; ARNTL2; MYB; ZBTB18; ZNF184; FOSB; ID4