Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16540 Azd-8330 GSE70138 MCF10A Human 3h 0.04uM EID0007
Types Number Response transcription factors
Up-regulation 281 ZNF586; PLAGL1; KAT2B; FOXL2; MYBL2; LZTS1; EMX2; TCEA1; OSR2; TFEC; AHR; NR1H2; MNAT1; RBPMS; KAT7; BNC2; NR2F1; WT1; NFX1; KLF10; ZNF672; DAXX; HMBOX1; TEAD4; ELK4; ZNF384; MTF1; KAT6A; CNOT6; PML; CHD3; EBF2; WNT4; PKNOX1; EGR4; MAF; GATA2; TOX; RARG; BLZF1; BPTF; PEG3; STAT4; ZNF589; SERTAD2; SMAD1; CEBPZ; MDFI; ASH2L; IRF4; ZNF835; LIMD1; SMARCD2; NFATC3; SP2; ZNF292; BATF; NANOG; ZXDC; GON4L; VGLL1; ZFPM2; ZNF75D; ELK3; ERG; TFAP2C; DACH1; TSC22D3; HOXC4; ATF3; HMG20A; FOXI1; ONECUT2; SCMH1; TRIM16; THAP1; HOXD9; ZNF350; SMARCA2; BCLAF1; TMF1; ZEB1; MXD4; KLF7; SMAD6; NCOA2; RCOR3; ASH1L; ERBB4; ZNF175; HIVEP2; ZBTB20; PRMT2; PKNOX2; SOX13; ZNF696; ZNF467; ZNF248; MAML1; ZNF235; SMAD3; RARA; SHOX; NEUROD4; CREBL2; EGR2; NR3C1; VENTX; CDYL; PRRX1; PRDM4; NOCT; SOX5; NFYC; ARNT; TSHZ2; PBX1; ZFP37; CDK2; CBX5; CBX3; SUPT4H1; STAT2; ZNF512B; NFKB2; OVOL1; NFKBIB; ID4; DYRK1B; ZNF415; GATA6; LOXL2; ZNF623; GTF2I; MEF2D; PRDM1; LMCD1; PLAG1; ING1; SRY; CAMTA1; MBD1; MYCL; DR1; CBX2; ZNF556; EPAS1; TWIST1; RAD21; ZIC3; CREBZF; PRDM5; NKX2-1; EGR3; REST; FUBP1; RARB; BTG1; POU5F1B; MEOX1; ZEB2; DNAJC2; SIX1; WWP1; CHD9; CREB3L1; NHLH1; SP140; ZNF124; SMARCE1; MTA1; MGA; PROX1; TAF4B; HOXD3; ZNF227; E2F3; CLOCK; ZNF552; ZNF302; RSF1; ZNF529; FOSL2; LIN28A; MYT1; KDM5B; CIITA; ZNF528; ZNF764; CBX4; NR5A2; AEBP1; SPDEF; KLF2; LHX2; IRX5; GFI1; MED12; IRF9; BRWD1; PMF1; ZNF329; NR1D2; PRDM14; SETDB1; SAP30; DDX5; HIVEP1; BACH1; ZNF423; EN1; MYB; TBL1XR1; ATN1; ZNF516; ID2; TULP4; TFDP2; SNAI1; RFX5; TOPORS; MYCN; TOB1; ESR1; ARL2BP; ADRB2; TBL1X; PRDM2; WWC1; ZNF134; TCF21; MITF; ZNF222; HDAC9; NCOA1; IL16; ZNF571; NR4A1; ZNF200; PAX8; SOX17; TLE4; ZNF606; SMARCA1; ISL1; ZBTB18; NR4A2; SATB1; ASCL1; HIC2; TRPS1; ZNF44; ZBED2; NFATC1; NPAT; HLF; HOXB6; STAT5B; CREM; ZSCAN31; REL; ZNF267; ZNF184; CCNA2; TOX3; TCF4; DBP; IRF7; TFAP2A; FOXJ3; RBFOX2; LPIN2; ZNF551; FOSB; BASP1; NR2F6; HOXB7; CREB1; BHLHE41; TRIB3; MAFB
Down-regulation 151 CDK7; YBX3; HMGA1; HMGA2; CEBPB; MED27; ETV4; CHD1; ZMYND8; ABL1; JUNB; HTATIP2; TGIF1; SOX9; ARID5A; ZNF160; ETV5; YBX1; ZBTB16; BRPF1; AATF; HHEX; MMS19; DDIT3; EHMT2; UBE2B; ZFP36L2; HEY1; TADA3; NOC2L; BRD3; BRD8; ACTL6A; MLXIP; SSX1; RUVBL2; EGR1; HMGB1; RUNX1; SAFB; PITX1; PDLIM1; ZNF131; ZMYM2; HDAC1; TCEB2; ZNF202; KLF1; SNAPC4; ZNF195; NFE2L1; FOXK2; IKBKAP; TP63; ZNF721; ZZZ3; TGFB1; CRY1; CNOT2; BTF3; TAF9; MDM4; MYC; SP100; PIR; MED24; MDM2; BRD4; ARID1A; ZNF410; TRIM29; EHF; CIZ1; CEBPG; FLNA; MBD2; RBM39; NFE2L2; UBP1; RNF111; APEX1; SPEN; EZH2; ARID5B; MTF2; RNF6; RREB1; PRKDC; BANP; YEATS2; KLF5; ZFP64; UBE2I; BBX; FOXF2; GTF3A; NKX3-1; ZNF331; FOSL1; MKL2; EDF1; PIAS1; ZFP36L1; CBX6; TRIM28; PEX14; GFI1B; CREB5; BACH2; ZNF107; NR2F2; PCGF2; TLE1; POU2AF1; NPAS2; AFF1; RXRA; RBBP8; E2F8; DMTF1; JUP; MED1; ATF4; PAX5; XRCC6; ELF5; FOXC1; TGFB1I1; PSIP1; TLE2; HNRNPD; SCAND1; THAP11; ZNF93; MAGED1; FOXG1; MECOM; PPARG; PTTG1; ZNF91; HIRA; BAZ1A; ARNTL2; GATA3; ZNF43; MXI1; TBX2; ZSCAN18; MEF2C; BCL11B; ZNF430