Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16539 Azd-8330 GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 238 SREBF2; BTG1; IRF4; SREBF1; CLOCK; ZNF580; ZHX2; ITGB3BP; ZFY; BRF2; GLI1; CBX7; ASH1L; ESR2; VGLL4; KDM5D; NR2F2; RXRA; THRB; ARID4A; NCOA2; IKZF2; MYBL1; ADNP; UBP1; KLF12; SRCAP; ZNF215; TFCP2L1; HOXD11; POU2F1; SIX2; NR3C1; STAT4; CHD3; ELK1; NFIX; UBE2L3; MED13; MAZ; KAT2B; NR1H2; KLF15; TXNIP; RERE; PRRX1; TOB1; NHLH1; EN2; TOPORS; POU6F1; FUBP1; CCNT1; PEG3; CIITA; TAF5; HDAC7; CREB3L1; AFF2; WHSC1L1; CTBP2; SIN3B; ZNF816; EZH1; TBL1XR1; ZBTB38; ZMIZ1; MSC; SKI; NELFB; NFAT5; ZNF688; SSBP3; E2F2; ZNF324; STAT6; ING4; NFX1; NR3C2; TSC22D4; NCOR1; MED25; GATAD2A; SHOX; POU5F1B; ZNF507; PRDM1; RARG; ETS1; ZNF506; TAF6; TGFB1I1; VENTX; ZNF175; E2F1; NFKBIB; LZTR1; HMGXB4; PBX1; POU4F1; LIMD1; CALCOCO1; PAX1; SMAD5; TRIM33; AR; EHF; RBL2; RCOR3; HOXC11; ZNF224; ZEB2; TEAD3; FOXI1; RBBP7; PIAS3; ZNF248; RAD21; BNC2; HNF1B; EN1; ZNF222; NR4A2; ZNF611; BCL6; ZBTB7A; JUP; RBPMS; FOXN3; ZMYND8; NEUROD2; ZKSCAN7; ID2; PRDM2; MEIS2; ZNF665; EPAS1; ZMYM2; TERF1; NFATC3; TRIP6; ZNF329; TFEC; SNAI1; TBL1X; ZNF124; ARID4B; CIZ1; SMARCA2; TRIM32; THRA; PDLIM1; MBD2; DLX5; NFATC4; ZSCAN18; SATB2; ZNF544; HLTF; HDAC9; PRRX2; ZNF331; ZNF223; OVOL1; HOXC10; ZNF160; TCF4; VEZF1; E2F8; THAP11; ERBB2; CITED1; ZNF274; SPIB; GATA6; ELF3; POU2AF1; PAX5; NFKB2; SSX1; ESR1; ZNF606; MECP2; HIVEP1; AEBP1; EMX2; TP63; CHD9; BACH2; ZNF573; ZNF394; PURA; SIAH2; SATB1; TAF1; CREBL2; NR2F1; SMAD7; NEUROD1; NPAS2; NCOA1; HIF1A; WT1; SALL2; ZNF226; STAT1; ZNF83; ZNF302; LITAF; RNF141; MAF; ZNF217; KLF9; TFAP2A; CDK8; CREM; SMARCB1; ZNF44; TRPS1; BCL11A; MEIS1; PAX6; PAX8; NR2F6; ZNF184; HOXC6; ID4; BASP1; ZNF264; LPIN2; NR1D2; ZNF267; INSM1; CREB1; SNAI2; ZFP36L1; TRIB3; IKZF1
Down-regulation 165 PUF60; ZNF202; CEBPB; NFE2; MYC; DDIT3; PITX2; EGR1; HMGN3; FOSL1; HEY1; RNF4; ELF1; CEBPD; USP16; NCOA4; NCOR2; ETS2; RFC1; TBPL1; TAF9; YAP1; PSMC3IP; IRX4; ZNF22; ZNF24; PAXBP1; ZNF410; ZNF165; SOX9; MED17; KLF6; NFIB; TEAD4; BTF3; WHSC1; GTF3A; HHEX; HAND1; ZKSCAN5; RUVBL2; CHD7; BRIP1; CREB5; CCNC; RUNX1; ZNF281; ARID5A; HTATIP2; ISL1; MYF6; ZNF268; ABL1; TRIP4; CCNA2; MNDA; SIX3; HDAC1; MTA1; ZZZ3; MEOX2; BIRC2; ARID3B; PATZ1; PLAGL2; ERG; MED6; EGR4; MED27; APEX1; DPF2; TLE1; MLLT10; ZFX; FHL2; NKX3-1; HNRNPD; TAF1A; FOXM1; TFCP2; NRBF2; ADRB2; BAZ2B; CAMTA1; MED24; ZNF227; NFYA; TAF1D; CITED2; L3MBTL1; TCF7L1; NKX2-1; STAT3; ILF2; PTTG1; KAT6B; TSC22D1; SF1; SMARCE1; UBE2I; NONO; BLM; ZNF200; MYCN; ATF4; THAP10; ASH2L; IRF7; CERS6; CTBP1; MYCL; TOX; SOX11; MTF2; HMGB2; ID1; PHIP; RBBP4; PROX1; ZNF7; CENPF; FOXJ3; ZFP36L2; TAF9B; RBPJ; NEDD8; ZFHX4; ZNF195; ZNF516; BRD2; JUND; NKX2-2; ASCL1; ZNF107; HLX; TAF10; CARHSP1; CEBPA; XBP1; ZBED2; WWC1; ZSCAN31; FOXG1; PITX1; FLNA; ECD; CALR; DACH1; MECOM; SPEN; FOXO3; HMGB1; PBX3; FOSB; STAT5B; ARNTL2; HIRA; ZEB1; EGR3; KLF4; EGR2; SCAND1; BHLHE41; RFX5; TBX3