Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16537 Azd-8330 GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 79 GATA6; PBX1; TSC22D3; HMGB2; MEF2C; GATA3; RBBP7; SSBP2; MAGED1; IRF4; ELF2; ASCL1; RBBP5; GATA2; CITED2; BTG1; MDM4; TGFB1; ISL1; REPIN1; HMGN3; THAP10; MBD2; SUB1; IRF9; WNT4; NR3C2; TRIM16; ZNF512B; RBPMS; ELF1; PIR; SSBP3; CREB3L1; CENPF; ERBB2; TCF4; NR5A2; IRF8; HNRNPD; HLF; BAZ1A; AEBP1; OSR2; FLNA; TXNIP; YWHAB; MAZ; ID3; SATB1; SOX12; AFF1; SFPQ; AES; POU2AF1; TBX2; SPEN; ZNF467; SAP30; TWIST1; ELF5; NFKBIB; MNDA; SPIB; IFI16; MXI1; HES1; SOX11; TRIM22; TLE1; PEG3; ID2; NR2F6; THAP11; KLF4; NR1D2; KDM5D; TBX3; HMG20B
Down-regulation 48 ETV4; FOSL1; MLX; ELK3; NR1H3; E2F3; BATF3; MYC; NAB1; RUNX1; KLF7; BAZ2B; RYBP; ETV5; ZNF266; LOXL2; BHLHE40; BRD7; MAFF; ZNF22; TGIF1; TERF2; WWTR1; ATF3; CHD9; DLX2; LPIN2; TRIB3; FOXD1; PURA; CREG1; ZNF189; WT1; ZNF217; HOXC10; NRIP1; ZFP36L2; ARID4B; LEF1; HTATIP2; ARID5B; HOXB6; NCOA1; ZIC1; HOXB7; ESR1; ZSCAN18; IKZF1