Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16536 Azd-8330 GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 92 CDK9; NFIC; BRD4; SSBP2; SLC2A4RG; ZHX2; PITX1; HOXB13; ZBTB7B; HNF1B; CDIP1; SOX13; TBL1X; PHIP; LMO1; MYCL; EVX1; ZNF611; ZNF160; CALR; ARID5B; CENPB; BARX1; PNRC1; SIX6; ZBED1; CTBP2; THRA; TLE4; RBPMS; FOXO4; SPI1; AR; EHF; PLAGL1; SOX12; KDM5B; TOX; GATA6; RBBP5; SPEN; TLE2; CSDC2; ING4; ATN1; SOX2; HMGN3; CHD8; SMAD1; CITED2; FOXF1; SUMO1; VGLL1; NFIB; RFX5; ZNF721; BBX; TGIF2; ZSCAN31; PDLIM1; THAP11; CUX1; NONO; FOXF2; SMAD6; HLX; CRYM; ZBTB38; ERBB4; PBXIP1; ZNF329; STAT3; INSM1; PAX6; ING3; ZNF44; INSR; HMGB3; TULP3; TGFB1; JUND; HOXC10; ZSCAN18; GLI2; JUP; NR2F6; DACH1; RBBP8; HOXD1; TOX3; MAF; TRIB3
Down-regulation 56 HMGA2; TSC22D1; WWTR1; GTF3A; ELK3; MYC; HMGA1; FOSL1; SSX1; ABL1; LIMD1; MTF2; RNF6; ZNF410; CEBPB; KAT6B; EGR3; BHLHE40; ELF1; SMAD2; CREG1; PRRX1; RBPJ; ZNF589; ID1; MAFF; EYA2; CEBPG; CTNNB1; SAP18; HOXA5; TLE1; ZEB1; TGFB1I1; HDAC4; HOXB7; HIC2; AFF1; MNDA; ZFP36L2; ZNF131; DLX5; STAT4; BASP1; JARID2; LOXL2; SOX11; ARNTL2; TXNIP; HOXC6; TFDP2; STAT1; BCL11B; SNAI2; ID4; HOXB6