Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16535 Azd-8330 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 57 KLF6; RBPMS; MED14; CHD9; YEATS4; TCF4; IRF4; NKX2-1; ILF2; CLOCK; MXD4; TSC22D3; AR; NFATC3; SOX4; PHIP; HLTF; HMGB3; CUX2; SALL2; NLK; CDX1; GATAD2A; TFAP2C; HTATIP2; RSF1; ZNF329; ZNF124; AEBP1; ZNF195; IRF8; NKX2-2; TMF1; ESR1; XBP1; WNT4; INSM1; DACH1; ZBED2; ASCL1; IRF9; ZNF415; SOX12; IRX5; SPIB; TCF7L1; ARL2BP; PDLIM1; POU2AF1; TRPS1; JUND; HMGN3; PAX5; TRIM22; TWIST1; TRIM29; NR2F6
Down-regulation 60 HMGA2; SP140L; FOSL1; DDIT3; MYC; JUNB; CNOT2; FHL2; LEF1; YAP1; FOXO4; ITGB3BP; SOX9; HDAC1; CBX7; IKBKAP; ZNF24; TCEB2; MED21; EMX2; ZNF263; CEBPG; BBX; CEBPB; MTF2; TRIM16; ABL1; NR2F2; RXRA; ARNTL2; ZMYND8; TRIB3; NKX3-1; BCL6; FOXG1; FOXD1; NFE2; CCNC; RNF6; BRD2; TBL1X; TCF7; ECD; SPEN; MECOM; FOXO3; EGR3; PSIP1; CREG1; HOXB7; MXI1; HOXA10; SCAND1; JARID2; ZNF200; HOXC6; FOXF1; MSX1; BCL11B; IKZF1