Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16530 Ldn-193189 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 70 TSC22D3; EGR1; NFKBIA; ATF3; NFIL3; KLF6; JUN; NR4A1; NFKB1; HMBOX1; FOSB; MTF1; NR3C1; SMARCD3; SOX4; ZBTB17; NR4A2; JUND; TSC22D1; ID2; DACH1; TCEB2; XBP1; ARID4B; FOS; PNRC1; KAT6B; CDX1; GATA6; WNT4; KDM5B; NR3C2; NR2F1; PLAGL1; HBP1; AEBP1; CERS4; FOXF1; BHLHE40; FOSL2; KLF4; MAFF; ETS2; TOX; CUX1; RELB; HOXA5; NR4A3; SOX11; ZFPM2; CEBPD; SPEN; FOXF2; ZBTB20; MXI1; MEIS1; FOXO3; ZSCAN31; PSIP1; TLE4; TSC22D2; REL; IRF8; KLF2; MTA1; MSX1; NR2F6; BASP1; ZFP36L1; TRIB3
Down-regulation 73 FHL2; ABT1; BRCA1; EED; GTF3A; ELF2; E2F8; EZH2; TRIP4; NR1H3; WDHD1; HOXA1; TEAD4; E2F3; SP3; ITGB3BP; SMARCA2; TXNIP; ZNF266; BRIP1; ZNF239; MYC; NUP62; EN1; ILF2; DEK; TBL1XR1; USP21; HMGA1; HOXA10; RNF6; MYBL1; COPS2; FOXC1; MKL2; AFF1; HOXD11; NFE2L3; SUV39H1; ELF5; DLX5; NANOG; TP63; ZFP36L2; BIRC2; CCNA2; HOXC10; XRCC6; TFAP2C; DEAF1; NPAT; NR2F2; PDLIM1; ZBTB18; JAK2; NKX3-1; SNAI2; RBBP8; ESR1; MNDA; HOXC6; HOXB7; PAX8; SCAND1; TRIM29; ZNF274; ZNF184; IRF6; FOXJ3; BCL11B; BHLHE41; HOXB6; ZNF91