Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16527 Cgp-60474 GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 177 PFDN5; TCEA1; STAT2; ZNF117; ZNF177; PAX8; PBX1; RERE; POU5F1B; EZH2; CERS4; HDAC5; ZNF253; PRRX1; HEY2; NANOG; BCL6; MEOX1; CALCOCO1; ZNF589; L3MBTL1; HMBOX1; KAT2B; ZNF711; ZNF692; NR0B2; ST18; ZNF415; TEAD4; ING4; ZNF688; IRF9; PCGF3; EPAS1; SOX11; ZKSCAN7; MYT1; ZNF667; RING1; ZNF107; MYCL; RB1; LZTR1; ZBED2; ZNF93; NFATC3; ZNF665; ERBB4; ZBTB44; SUMO1; TADA3; CNBP; MYCN; ZNF83; SP100; EZH1; ETV5; GRHL2; ZNF273; NFIB; TAF1C; MZF1; EN1; GTF2I; NKX2-2; OLIG2; MBD4; ZSCAN18; SHOX2; NFIC; ZNF532; NR2C1; TCF4; SOHLH2; AR; CITED1; SSBP3; SOX10; BACH2; BAZ2A; EHF; MED12; AES; ZNF529; FOXO4; KDM5C; PKNOX2; TRIM25; CREBL2; PBX3; NR1H2; ZIC3; ZNF248; SIX1; DLX5; ZMYND8; SALL2; FOXN3; SMAD3; ZIC1; ZNF239; ATF3; CBFA2T2; SNAI1; ZNF33B; ZNF43; ZNF91; CREB3L2; FLI1; CUX2; KLF4; PAX6; SMARCA1; FOXG1; SIX2; MYBL1; HLF; ZNF85; ZFPM2; TRIM24; HBP1; TRPS1; HOXB2; MYRF; IRF4; HSBP1; LIN28A; ZNF571; ZNF606; VPS72; PBXIP1; IL16; PRDM2; BHLHE41; PSIP1; NR0B1; SATB1; ZNF423; PEG3; XRCC6; WWC1; ZNF131; RBBP8; ASCL1; BCL11A; FOXE1; TCF7L2; NFATC4; NEUROD1; FOXF1; IRF5; MXI1; DACH1; AEBP1; HMGN3; TRIM22; ZNF232; MEIS2; SOX17; JUP; NR2F6; ZEB1; HMGB1; DNMT3B; MEIS1; MTA1; ZKSCAN1; TFDP2; FOSB; MSX1; TWIST1; CREB1; INSM1; ESR1; MECOM; TRIB3; ID4
Down-regulation 88 MYC; NFKBIA; NFIL3; ABT1; EED; ELK3; FOSL1; ELF1; NUP62; FHL2; MAFF; HOXA1; NRIP1; FOXO3; RNF4; FOXO1; PPRC1; BIRC2; CHD4; CEBPD; TSC22D2; EGR3; RNF6; TBP; RCOR1; BCL10; ZBTB1; ZNF281; TSC22D1; SNW1; ADRB2; ELF4; SMAD7; RUNX3; FOSL2; NFKB1; NKX3-1; HOXA10; HMGA2; RUNX1; BHLHE40; HMGB3; MED6; RREB1; DR1; PUF60; CEBPB; FLNA; HMGB2; VDR; TFAM; ERBB2; MED1; PIR; KLF10; KAT6B; ZFP36L2; IKBKAP; AFF1; SFPQ; ZNF12; SNAI2; BRD2; NR2F2; ID3; XBP1; CBFB; IRX5; SUV39H1; CDK8; ARNTL; TLE1; USP22; FOXD1; ID2; JARID2; ETS2; ID1; AHR; RFX5; IFI16; ZFP36L1; MAGED1; ZNF267; CCNA2; HOXC6; TBX2; BCL11B