Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16526 Cgp-60474 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 151 BNC2; GATA4; MKL1; MYRF; CITED2; TBL1X; NR1I3; HINFP; PBX1; AIP; ZBTB17; PBX3; NANOG; ZFPM2; CXXC1; NCOA2; LZTR1; SNAPC4; ZNF688; NR5A2; HSF4; EP300; AEBP1; SHOX2; ZNF835; GATA6; CHD3; ZNF654; ST18; SIX3; TAF6; PNRC1; NFIC; RERE; LHX3; PAX6; STAT2; ZNF667; OVOL2; ZNF444; PIAS4; SMARCA1; KAT2B; NAB2; HEY1; NR4A2; LHX2; SRY; ZMYND8; KLF15; FOXF1; MEIS2; NR1I2; ZNF692; ZNF711; PRDM2; BAZ2A; IRF1; TBX19; SMAD4; ZNF467; ZNF816; BARX1; SCMH1; FOXO4; ZBED2; IKZF1; CERS4; ZNF177; VENTX; THRB; BCL6; PAWR; REPIN1; ERBB4; CDIP1; CUX2; AR; THRA; SOX2; DMTF1; MECP2; NR1H2; SATB1; TTF2; ING4; KLF3; TCEA2; TWIST1; CREBL2; SSX1; NR2C1; ZNF141; KAT6B; FOS; BANP; PRRX1; TLE2; TGFB1I1; NR1H4; ZNF665; KLF13; PEG3; LOXL2; IRF9; TCF4; ZNF415; TCF21; JAK2; ZHX2; KLF7; AES; PITX1; KDM4C; IRF4; ZFHX4; NFE2L3; RBPMS; KDM5B; HLF; SALL2; ZEB1; LIN28A; CBFA2T3; ZNF117; NFATC4; TAF1; SSBP3; BCL11A; ZNF131; CREB3L2; MTA1; PHF1; NFATC1; FOXG1; THAP11; TCF7; CREM; GLI2; IRF8; ZNF91; CREB1; WT1; ZNF232; PPARG; FOXE1; NR2F6; TRIB3; MECOM; HOXD1; BASP1
Down-regulation 91 MYC; ADRB2; NUP62; E2F3; EED; FOSL1; BIRC2; NFIL3; TBP; FHL2; HMGA2; SNW1; NR2F2; NCOA4; NFATC3; CBFB; SSBP2; C1D; AGO2; TBL1XR1; NRIP1; SMARCE1; PUF60; FOXC1; MTF2; ZFP36L2; BTG1; HTATIP2; TEAD1; PSIP1; RNF6; FOXJ3; XBP1; HMGB3; HSF2; CRY1; MED6; RBBP4; ELK3; EGR3; EZH2; ZNF22; SUB1; SUV39H1; ERBB2; SMARCA2; CEBPB; FOXO3; SMAD7; HOXA5; SIX2; EHF; NFKBIA; VGLL4; HOXA10; MED1; JARID2; ZNF443; MED24; SRF; TAF1D; NCOR2; ZNF12; MAGED1; EGR2; AFF1; NKX3-1; EYA2; ENO1; RUNX1; SAP18; IRX5; SMARCA4; BAZ1A; HOXC10; NRBF2; SOX9; USP22; RAN; ZNF267; RFX5; ETS2; TCF7L2; CCNA2; IKBKAP; TLE1; HOXC6; ID4; IRF6; BMI1; ZBTB18