Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16525 Nvp-aew541 GSE70138 MCF10A Human 3h 0.04uM EID0007
Types Number Response transcription factors
Up-regulation 224 ZNF586; SUV39H1; FOXP3; NR2F1; EMX2; RAD21; ZNF611; ZNF721; KMT2D; ZFPM2; PITX3; ETS1; KLF13; TUB; LHX1; ZNF135; FOXA2; ZNF415; ZNF205; NCOA6; ZNF124; DACH1; PBX3; RAX; NR4A2; ZNF337; HSF4; TAF5; ZNF160; ZNF606; PITX2; GTF2IRD1; BNC2; NR2C1; FOXL2; ZFHX2; AEBP1; TCF21; NFIC; ZNF177; ZNF268; TCF3; ETV1; TRPS1; NCOR2; ZNF432; ZNF562; FOXJ1; SIX6; SMARCD1; PLAG1; CDX1; ERBB4; HOXA3; KLF15; SOHLH2; PROP1; HOXB9; ZNF287; MXD4; AFF2; CSDC2; TBL1X; HEYL; HOXB13; ZBTB20; ZNF665; EVX1; NHLH1; ZNF219; PRRX1; RARA; ZNF506; ZNF250; CEBPE; ZBED1; NFATC3; WT1; PAX1; ZNF671; ZSCAN2; ZNF580; NCOA2; HOXD3; PCGF3; TCF15; ESRRG; SMAD6; MDM2; ZNF248; ZNF79; SKI; TCEA2; ATOH1; ZNF93; PRDM10; PRDM12; MED12; TULP4; GBX1; FUBP1; EPAS1; ZSCAN18; NKX2-1; TBX1; ST18; HMGB3; TCF4; PRDM1; CDIP1; ZMIZ1; SOX18; ZNF667; IRF9; HOXC4; HOXB1; ZNF117; ZNF587; TOX3; NFKBIB; ZNF669; ESR1; NFIX; ZBTB16; ZNF701; ZNF44; HMGB2; SMARCC2; SPI1; CUX2; AR; VDR; ZNF141; ZBTB38; FLI1; KDM5C; MZF1; WNT4; THRA; MYT1; PEG3; ZNF253; SALL1; ZNF304; ZNF43; CUX1; CREB3L2; ZBTB44; SNAI1; ZNF544; SMARCB1; LEF1; ZNF91; BARX1; NFATC4; CITED1; SOX13; ZNF232; NEUROD1; NFAT5; MYCL; ZEB1; SPDEF; ARNT; SOX17; FOXG1; BANP; ZNF329; ZNF532; ZNF85; CEBPD; ZNF273; ZNF107; PROX1; TBX3; CHD9; ZBTB43; STAT1; NHLH2; ZNF331; HBP1; MYRF; TGIF2; PIAS3; ZNF350; MLXIP; BACH2; ZKSCAN1; CTBP2; ID4; BCL11A; RBBP8; KDM5A; MEIS2; HLX; OSR2; HOXD1; ZNF131; PAX8; PGR; SPEN; RREB1; MTA1; ZNF189; CREM; MKL2; NR2F6; PBX1; IFI16; LMCD1; ZNF426; ZIC1; ID3; ZNF264; ZNF443; KLF9; ZNF551; POU2AF1; TLE4; CREB1; VPS72; SNAI2; ZNF430; TRIB3
Down-regulation 60 TSC22D1; EED; ELK3; KAT7; RNF138; YBX1; ATF3; HLTF; ELF1; HMGA1; CNBP; EZH2; JUNB; NUP62; HOXA1; ERCC3; SHOX2; SUB1; CEBPB; RUVBL2; SREBF1; RYBP; ISL1; BRD2; AHR; TRIM28; PUF60; KLF10; C1QBP; TRIP6; NKX3-1; CCNC; DNMT3B; LITAF; HHEX; PTTG1; USP22; NRBF2; RNF6; ERBB2; PSIP1; ECD; FLNA; NFKBIA; FOXO3; SCAND1; STAT3; TLE1; EGR3; JARID2; ADRB2; ARNTL2; IKBKAP; HOXC6; SATB1; RFX5; ABL1; BCL11B; CCNA2; BASP1