Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16524 Nvp-aew541 GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 49 SETD2; TCEA1; RBPMS; TSC22D3; RBM39; FOXD1; RNF138; DNAJC2; MNT; TRIM16; ELF3; CENPF; SMARCD3; HLTF; NUP62; TRIM28; PITX1; NR2F1; KAT6B; MED24; JUND; NR1H2; ATF3; TBL1X; BIRC2; TRIM24; RUNX3; FOSB; KDM5B; SOX9; MTDH; MYRF; PSIP1; HOXA5; ZNF274; TWIST1; PIR; GMNN; RBPJ; KDM5D; MTA1; ABL1; PPARG; CRK; TRIM29; BASP1; KLF2; ZBTB18; TRIB3
Down-regulation 63 CEBPB; MYCN; ZNF266; ZBTB16; ZNF384; RERE; DLX2; RUNX1; CEBPD; FOXO1; PSMC3; ZMIZ1; BAZ2B; NFAT5; NKX2-2; HIPK1; RNF111; DLX5; SMAD1; ZNF562; BLM; RFX2; ZNF165; ZHX2; ZBTB20; PNRC1; MEIS1; TULP4; ZNF516; FLI1; ACTL6A; SKI; MLXIP; PBX3; ARID4B; E2F2; PGR; HIVEP1; TERF2; TXNIP; CBFA2T3; IRF9; TULP3; CEBPA; TFEC; HOXC10; KLF5; FOXC1; GATA6; PRDM2; ERBB4; ZEB2; LEF1; NPAT; ZNF232; NR4A3; ZNF264; SATB1; IRF6; INSM1; MEIS2; PEG3; BCL11B