Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16523 Nvp-aew541 GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 79 TSC22D3; NFIB; GATA3; RBPMS; MDM2; WWTR1; NR2F1; ESRRG; SOX9; ZNF589; SMARCD2; TRIM16; MEF2C; SMAD5; SREBF1; STAT2; TFCP2L1; ZFPM2; MNAT1; GTF2I; HIPK2; FOXI1; NFE2L3; KAT2B; ELK3; HEY1; SIX1; CEBPZ; ZBTB38; ST18; NCOA2; LHX2; TGFB1; AR; SATB1; NR4A2; ELF3; ZNF721; SOX4; TP63; ZMYND8; KDM5B; PDLIM1; AHR; PBX3; BRD4; LITAF; PRKDC; BASP1; SOX2; KDM5D; TCF4; PBX1; FOSB; FOXO3; RBL2; TCF21; ZBTB16; HOXB2; PAX6; ZNF532; ZNF217; MYRF; DACH1; HHEX; ERBB2; WWC1; VPS72; HOXA5; HOXB5; ASCL1; IRF2; FOXF1; TRIM29; TXNIP; HOXB6; HOXB7; TRIB3; NR2F6
Down-regulation 79 PQBP1; NR3C1; RCOR1; MLX; SIRT7; SP140L; STAT6; MED21; KLF10; KAT6B; EYA1; MYCN; GATA6; ZZZ3; EYA2; RNF14; BTAF1; ZBTB11; ZNF107; NCOA4; HMGA2; ZMYM2; HOXA10; ZNF32; MYCL; LEF1; NFE2; DDIT3; ADRB2; YAP1; ZMIZ2; IRF9; CREB1; WNT4; PURA; CRY1; TBX2; ARID4B; SALL1; IKBKAP; MEOX1; BAZ1A; TAF10; APEX1; MSX1; NKX3-1; SFPQ; CARHSP1; PGR; NR0B1; NRIP1; NRBF2; TLE4; STAT4; ZNF443; JARID2; ID1; SNAI2; ZSCAN18; IFI16; TBX3; BCL11B; FOSL1; ID4; GATA2; TCF7L2; ABL1; WT1; HOXC6; ZNF551; PPARG; FOXJ3; ZNF423; STAT1; ZNF91; MAFB; MYB; PEG3; KLF2