Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16522 Nvp-aew541 GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 72 E2F2; TSC22D3; ATF3; EGR2; ETV1; IKZF4; POU5F1B; FOXC1; KMT2D; ETV4; APBB1; MYCL; ZNF415; NR2F1; TSC22D4; MSC; SOX9; BCL6; FOXJ1; AR; PRRX2; MAFF; BTG1; CUX2; ZNF528; PIR; EN1; NFATC3; SOX13; SIM2; EPAS1; EYA2; HOXC4; TP63; AHR; ZNF589; DDIT3; SOX15; HMGB3; SNAI1; NR4A1; HOXA5; NPAS2; MITF; NR0B1; NKX2-2; TLE2; PTRF; TFEC; HMGN3; FOXG1; PDLIM1; ATF4; RUNX3; MTA1; CALR; ZNF532; FOXF2; SMARCA1; ZNF232; ZIC1; KLF9; MAFB; HOXB2; TBX3; TOX3; ZSCAN18; FOXF1; TWIST1; TRIB3; KDM5D; ID4
Down-regulation 58 NFE2L2; MED6; BRIP1; CHD7; CHD1; EMX2; ZNF160; BAZ2B; SIX3; SP100; SP3; RREB1; ZHX2; HMGA2; ZBTB1; INSR; HHEX; NFKB1; HIVEP2; ZNF721; OSR2; PCGF2; ZNF281; TGIF1; TGFB1I1; CREB5; CEBPG; KLF11; E2F8; SMARCA4; ZNF107; SMAD1; POU2AF1; FLI1; NFE2L3; MNDA; YBX3; JARID2; LOXL2; TXNIP; NR2F6; TLE1; ZNF44; MYT1L; WWC1; TCF7; ZBTB18; ZEB2; GFI1; ADRB2; STAT1; BASP1; HOXB7; ZEB1; ZNF267; ZNF184; ZNF430; ZNF91