Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16520 Pf-431396 GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 67 NFIC; SP100; PEX2; KDM2A; HMBOX1; ZNF589; KLF13; SLC2A4RG; TRIP6; SMARCD3; CREB3L2; SMARCA1; BRD4; IKZF1; NR1H2; SOX13; PRDM10; EMX2; NR2F1; CDIP1; RUNX3; ZBTB38; HLTF; CUX1; KDM5C; HIPK2; NPAS2; MEIS2; PIR; MKL2; ZNF415; RSF1; ARNTL; E2F5; NFAT5; TRPS1; TOB1; HDAC4; FOXG1; HMGN3; TRIM22; HEY1; TBL1X; CRYM; MYT1L; PIAS1; NFATC4; ZNF331; SALL1; CREM; SOX17; HOXA5; MSX1; PBX1; INSM1; PEG3; HES1; FOXF1; VPS72; ABL1; ID3; NR2F6; ESR1; DBP; MECOM; TBX3; TRIB3
Down-regulation 64 YBX3; ATF3; CAMTA1; SOX11; YBX1; SHOX2; POU4F1; NFE2L3; FOSL2; PAWR; PCGF2; MED1; MEOX2; HOXD10; TRIM16; MAFF; SAP18; MED6; ZIC1; FOXN3; NCOA4; ELF3; PRRX1; EZH2; DLX2; KLF6; POU2AF1; HOXD11; EDF1; EHF; E2F8; ETS2; HDAC9; IRF8; DEK; ISL1; ERG; KLF4; BACH1; JUP; CEBPA; CITED2; FOXO3; TLE1; GTF3A; ZFP36L2; TOX3; BHLHE41; IKBKAP; RFX5; LMCD1; MAF; MAGED1; SCAND1; MYB; CARHSP1; HOXB7; HOXC6; MAFB; ZSCAN18; HOXA10; ZNF274; KDM5D; KLF2