Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16518 Pf-431396 GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 51 CUX2; MAFG; SND1; CREB3L2; HMBOX1; SOX2; ARID3A; TRIP6; MYRF; HDAC9; GATA1; SOX4; ZNF415; GATA6; ACTL6B; SOX13; PEG3; XBP1; CRYM; HIC2; SOX10; NR1H2; HBP1; HOXD3; ZNF423; ZNF117; HOXA5; PAX5; SPEN; ZIC1; SOX9; ZNF131; POU2AF1; MYT1L; VPS72; ATF4; MTA1; MECOM; IRF8; TRIM22; ST18; ERBB4; HOXD1; ZNF232; AEBP1; HES1; FOXJ3; TBX3; TWIST1; NR2F6; TRIB3
Down-regulation 56 ARID4B; HMGA2; NR2F2; TRIM32; MAX; BAZ2B; SMAD1; TCEB2; REPIN1; CTBP2; YBX1; MED1; PCGF2; WWTR1; TFAP2C; TLE1; RFX5; MED24; RBL2; CTBP1; ASCL1; FLNA; SOX11; HIRA; KLF4; DACH1; YBX3; BRD2; HMGB3; ADRB2; TCF7L2; ZSCAN31; TLE4; CREG1; NRIP1; ZFHX4; MAF; TSC22D2; CARHSP1; IKZF1; WT1; ZNF148; HOXC10; GATA3; HOXC6; PAX8; TXNIP; KLF2; MSX1; STAT4; ZNF652; SCAND1; DBP; TBX2; BCL11B; MAFB