Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16516 Pf-431396 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 40 MXD4; PFDN5; SND1; PEX2; CNBP; KDM5A; SP110; NCOA2; CAMTA2; OVOL2; NFIB; CDIP1; HDAC5; NFATC4; SOX4; HLTF; TOX; PITX1; TRPS1; EMX2; TWIST1; PBX1; TAF10; SPDEF; ENO1; ZNF532; TRIP6; PDLIM1; JUP; PSIP1; KAT6B; FOXG1; NEUROD1; ESR1; SPIB; HOXC10; RFX5; VPS72; MECOM; TRIB3
Down-regulation 86 MYC; SUZ12; HOXA1; ZNF202; FOXO3; ADRB2; NFIL3; NFKB1; FOSL1; FOXO1; ELK3; NFKBIA; PHF8; EZH2; ZBTB39; ZFP36L2; JUNB; EED; ZBTB1; RNF111; BLM; KLF10; HSF2; ZBTB16; PLAGL2; CCDC59; TRIM32; BAZ1B; HMGA2; ZBED1; SMAD7; TSC22D2; TGIF1; RNF138; NKX3-1; ZNF107; DDIT3; ARID4B; NRIP1; BIRC2; ARID1A; HIC2; RBM14; REST; RRN3; NUP62; HOXA5; SUV39H1; IKBKAP; MAFF; CITED2; TRIM16; PURA; TAF7; ETS2; SIAH2; DNMT3B; ZNF443; EGR2; CHD7; FOXC1; ZNF267; EGR3; RREB1; CDK8; INSR; GFI1; NPAT; KLF5; AHR; SOX11; ZEB2; TCF7L2; HOXA10; HOXC6; ZBTB18; ID2; JARID2; ZNF85; MNDA; MAFB; BHLHE41; ZNF43; ZNF652; ZNF430; SNAI2