Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16514 Gsk-1059615 GSE70138 MCF10A Human 3h 0.37uM EID0007
Types Number Response transcription factors
Up-regulation 50 VGLL4; ZNF589; KAT6B; TSC22D3; TFCP2L1; ID2; CNBP; CDK9; PRRX1; NFIB; ZFP36L2; EHF; AR; CUX2; THAP11; TDP2; FOXN3; GRHL2; HBP1; AEBP1; TBL1X; RXRA; PBX1; TRPS1; HMGN3; ARID5B; TP63; RORA; MTA1; ZNF232; MKL2; VPS72; MBD2; TXNIP; ID3; MXI1; ZFP36L1; TOB1; MAF; ZNF91; HOXA5; HOXB7; ZNF43; TRIB3; MSX1; TRIM22; MAFB; TLE1; NR2F6; ID4
Down-regulation 30 MED1; DDIT3; CHD1; SIX2; ZNF721; NKX3-1; RYBP; CEBPG; BRD2; CITED1; CREB3L1; ADNP2; FOSB; BHLHE40; HIC2; EYA2; ING3; CEBPA; KLF4; MNDA; SCAND1; FOSL1; NRIP1; LEF1; MYB; STAT4; DACH1; HOXC6; KLF2; IKZF1