Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16511 Gsk-1059615 GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 123 TSC22D3; SETD2; RERE; BTG1; ZBTB17; PBX3; TCF4; HBP1; MXD4; PCGF3; SMAD1; SOX4; GON4L; ETV1; WHSC1; BNC2; ZFPM2; ESRRG; TLE2; KLF7; ZNF34; FOXN3; GLI3; ZNF532; FOXO1; CDIP1; FUBP1; BAZ2A; MEIS2; ZNF117; TCF3; CREB3L2; MED12; SMARCC2; KMT2A; SMARCD3; PRDM2; NR2F1; MNT; MLLT10; NCOA2; HEY1; PBX1; ERBB4; EZH1; PLAG1; WNT4; NFIB; TXNIP; BANP; TRIM29; CALCOCO1; KAT6B; JUP; ARID1A; AEBP1; TRPS1; ZHX2; MYRF; PNRC1; BCL11A; NFE2L3; HMGB2; GATA6; MLXIP; ZMYND8; ARID4B; SOX10; KLF6; BACH2; GATA3; ZEB1; ZBED2; NHLH2; GRHL2; ZNF83; ST18; TWIST1; PHF1; NR4A2; DACH1; TCF21; PAX5; ID3; MBD2; ELF5; MITF; MXI1; PSIP1; SPEN; NFATC1; ZNF93; HOXA5; ZNF665; ZNF131; CDK8; KLF11; RFX5; SATB1; SMAD3; HTATIP2; NFATC4; ID1; RBFOX2; MECOM; TRIB3; ZSCAN18; HMGB1; MEIS1; ABL1; MTA1; HES1; HOXD1; INSM1; ZNF85; TBX3; RBPJ; CREB1; VPS72; SNAI2; BHLHE41; ID4; MAFB
Down-regulation 58 FOSL1; HMGA2; SUZ12; EGR3; ADRB2; NCOA4; BIRC2; MYC; TBP; KLF10; RNF138; UBE3A; FHL2; NUP62; ZNF587; CTNNB1; NKX3-1; AATF; SSBP2; BHLHE40; ELK3; SUB1; IKBKAP; NRIP1; TRIM28; C1QBP; TRIP6; SMAD7; DR1; MAFF; EZH2; CCNC; JARID2; SIAH2; HOXC10; SFPQ; RREB1; ERBB2; KLF4; HHEX; SOX9; LOXL2; HMGB3; HDGF; IRF7; ZEB2; NR2F6; HOXC6; SCAND1; FOXJ3; FOSB; IRX5; HOXA10; EGR2; MNDA; ZFP36L1; KDM5D; IKZF1