Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16510 Barasertib-hqpa GSE70138 MCF10A Human 3h 0.04uM EID0007
Types Number Response transcription factors
Up-regulation 77 ZNF580; RARA; ETS2; FLNA; ZNF771; TGFB1; MDFI; CREB3L1; CTR9; PEX2; GATA2; SNW1; EYA1; HOXB9; NCOR2; PIR; POLR2A; MED6; IKZF1; ZNF22; SMARCE1; FOXA2; TCF20; ID3; HMGA1; TFCP2L1; TAF12; MED1; SIX2; SMAD6; HSF2; HLX; ISL1; MECOM; TFEC; ENO1; TRIM28; RBM14; PAX5; TOPORS; PTRF; CDX1; XBP1; CHD8; PRRX1; NPM1; NUP62; CREB3L2; HOXB2; HOXB6; ZEB2; ZNF226; CARM1; ZFHX4; SAP30; FOXD1; BRD2; SMARCB1; RAN; ZNF423; VDR; HMGB1; BASP1; KLF5; ID2; PBX3; MTA1; RBFOX2; TOX3; GMNN; HOXA5; RBPJ; HOXB7; HOXB5; HOXC6; KLF2; MAFB
Down-regulation 116 PUF60; PFDN5; HMBOX1; PSMC3; BAZ2B; HEY1; ZHX2; WWTR1; RNF138; NANOG; EP300; HHEX; ZNF217; ELF5; CHD1; RCOR3; HINFP; ELF2; DDX17; NFIB; ARID4B; NR2F6; TAF9; REPIN1; ZBTB20; ZBTB1; KAT2B; POLR3C; STAT2; ZNF500; COPS2; TRIM24; CBFA2T3; ZNF586; DDIT3; RBM39; MEOX2; FOXJ1; CCNE1; CAMTA1; KDM4C; LIN28A; ZNF512B; SIX1; ZBTB11; TBX2; SOX11; ZNF304; ELF1; ZNF350; AES; BHLHE41; MECP2; ZNF117; NCOA2; TSC22D2; HMGA2; TLE2; TAF10; SOX9; SOX4; INSR; ZNF532; CREG1; PRPF6; ZNF419; ATF3; CREB5; CITED1; RFXANK; BBX; IRF1; ZNF415; SMAD1; CUX2; HIRA; MYBL1; LEF1; RFX5; CTNNB1; PNRC1; ADNP2; PBX1; BRWD1; FOXG1; ZNF93; FOXE1; GRHL2; POU2AF1; ZNF302; PGR; ZNF43; CEBPA; TFAP2C; CALR; TLE4; ZIC1; PURA; RORA; ZNF652; KLF11; ZNF394; SALL2; WWC1; MAF; EGR3; ST18; ARID5B; GATA3; TBX3; ZSCAN18; ZNF274; ZNF91; ID4; THAP11; TFDP2