Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16509 Barasertib-hqpa GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 24 EMX2; PPARG; HLTF; NUP62; YWHAB; ASH2L; NCOA4; MAFF; SUB1; SOX4; FOSB; TAF10; STAT5B; RUNX1; STAT5A; PIR; AHR; JUND; LOXL2; ARID4B; TRIM29; SCAND1; TBX3; TRIB3
Down-regulation 69 YBX3; TTF2; RERE; PBX3; SOX11; BRCA2; NKX2-1; BRIP1; FOXI1; ZNF586; GRHL2; E2F8; ZBED1; ZBTB16; POU4F1; RXRA; TOPORS; FOXO1; TXNIP; MAF; GATA6; BCL11A; PBX1; FOXN3; PROX1; MYCN; BHLHE41; PRRX1; ARID5B; DLX2; ISL1; NR2F2; TCF7L2; ZNF83; NKX2-2; HEY1; NR2F1; BACH1; ZNF426; CTBP2; HHEX; ELF5; JAK2; FOXE1; LMCD1; CREG1; PAX6; TRPS1; TULP3; FOXC1; ZNF189; SPIB; KLF11; ZNF264; ARNTL2; ZKSCAN1; GFI1; REL; PAX5; ZNF551; POU2AF1; MYB; HOXB6; ID2; MXI1; ZNF652; ZNF184; MAFB; ZNF91