Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16508	Barasertib-hqpa	GSE70138	MCF10A	Human	3h	0.37uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	88	BRCA1; EED; TCFL5; MYBL2; SLC2A4RG; BBX; MTA2; HLTF; TCEB2; BAZ1B; POLR2A; DAXX; CCNE1; GATA2; EBF2; FOXO3; TCF4; TEAD1; GATA3; SAFB2; MXD4; CTNNB1; SNW1; KAT6A; EYA1; NKX3-1; SUB1; ELK3; MYCN; THAP4; NPM1; XBP1; ZNF587; HOXC6; DNAJC2; TBL1XR1; AES; TSC22D2; NR2F2; KLF10; RBM14; MBD2; TAF10; CREB5; ZNF721; HMGN3; SP110; HSBP1; KLF6; NUP62; LEF1; CREB3L1; RFX5; CBFA2T3; MAZ; FHL2; ESR1; FOXD1; BRD2; HEY1; ID3; AHR; TRIM16; MSX1; CBFB; GMNN; ZEB2; DMTF1; MTA1; ABL1; TWIST1; IRF8; WT1; TBX2; PA2G4; SPIB; SALL1; TRIM22; ZFP36L1; FOXF1; ID2; IRF7; TOX3; MAFB; KLF2; BMI1; SNAI2; TRIB3
Down-regulation	118	PUF60; ELF5; ZNF34; CITED2; ZNF654; NFIB; NFE2L3; PAXBP1; YBX3; PLAG1; OVOL2; PBX3; PPP1R13L; CCNH; ZNF165; SMAD1; ZNF133; TOB1; ELF3; NFIC; SP140L; TOX; HMGA2; ETS1; ZNF7; NANOG; AGO2; NR4A2; FOXG1; ZNF268; MECP2; ZNF331; MAFF; WWC1; MED12; ZNF623; CRTC1; RARB; ZBTB16; BHLHE41; LITAF; EN1; ZNF16; ETV6; RERE; NFIX; ATF7IP; JUNB; POU2AF1; TRPS1; JAK2; KDM4C; KDM5B; ZNF281; MXD1; ZNF510; ZNF302; CIR1; CBFA2T2; SOX10; INSR; NKX2-1; STAT3; FOXA2; EYA2; ZNF33B; FLI1; MXI1; BRWD1; NRL; LHX3; RBPMS; ERBB4; YBX2; FLNA; SMAD2; MYBL1; SPDEF; HHEX; ZNF43; ARID5B; CHD7; HIRA; ZNF589; NR2F6; ZNF232; RUNX1; TRIM29; ZNF532; CEBPA; FOXC1; EHF; MEIS1; PRDM2; NFATC4; PSIP1; XRCC6; PIAS1; TCF7L2; MYT1L; ZNF131; DEAF1; TAF1; LPIN2; BCL11A; ST18; ZNF45; SSBP2; ZNF200; RORA; ZNF184; MNDA; RBFOX2; MECOM; VPS72; ZNF85; DBP; ZNF91