Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16507 Barasertib-hqpa GSE70138 MCF10A Human 3h 1.11uM EID0007
Types Number Response transcription factors
Up-regulation 81 SUB1; FOXA1; BTG1; AR; GATA3; PPARG; PBX1; ADNP; HLTF; NR4A2; BCOR; ZNF415; IRF8; ARID4B; BCL3; ZBTB38; TERF1; TGIF1; LITAF; VEZF1; SMAD5; CERS6; PEG3; WWP1; ZBTB1; ATF3; TFAM; FOXN3; UBE2I; LOXL2; AFF1; MEOX1; YWHAB; TBX3; SOX11; HLF; ELF1; CREB3L2; BTF3; TOX3; HOXA10; REST; ZNF239; BASP1; TRPS1; TCF4; ID3; HBP1; TRIM16; EGR2; NCOA1; MTA1; SMAD3; HMGB1; RXRA; FOXF1; BAZ1A; SPIB; HMGB3; CHD7; MYBL1; MTF2; AHR; RORA; MKL2; FOXE1; KLF9; MITF; PDLIM1; NR1D2; SOX9; NEUROD1; VPS72; HOXB2; JARID2; RBBP8; ID1; ZNF430; ESR1; ZNF91; TRIB3
Down-regulation 51 ELK3; PRMT2; LYL1; MED21; CTBP2; TSC22D1; RFX7; TBPL1; TTF2; NR2F2; ZNF146; KLF6; PSMC3; PQBP1; HDAC9; CTNNB1; EMX2; ZMIZ2; ZNF423; TRIM27; ELF3; ETV6; PHOX2B; ERG; MLXIP; BCL11A; ARNTL2; BACH1; RNF141; PIR; MEF2A; SCAND1; CEBPA; FOXO3; PURA; BHLHE41; STAT3; CRYM; MECOM; ASCL1; FOXG1; SOX17; AEBP1; NRIP1; MAFB; POU2AF1; ZBTB18; LPIN2; ZNF274; HOXD1; HOXC6