Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16506 Barasertib-hqpa GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 51 RYBP; NPAS2; IRF1; CTNNB1; CNOT6; CCNT1; ID2; TRIM16; FOXO3; MED13; MDM4; GATAD2A; MYCN; JUNB; NR1H2; HSBP1; RBBP4; PTTG1; SUB1; BTG1; KAT6B; BRD2; XBP1; ZNF124; ZNF721; FOXD1; TBL1X; ERBB2; HMGB3; SALL1; CRY1; RNF6; SATB2; PDLIM1; HLF; LITAF; TSC22D2; TOX3; MTF2; ABL1; ZKSCAN1; HTATIP2; RBPJ; RFX5; BMI1; TXNIP; MEIS1; STAT1; ZNF91; TRIB3; MAFB
Down-regulation 99 PFDN5; VGLL4; BRIP1; MTA1; TCEA1; TOX; MED15; CNOT2; MMS19; OVOL2; SUPT7L; BRCA2; ZNF22; NFYB; PHOX2B; ZFP36L2; HMGA1; RARB; MLLT10; TSC22D1; PBX2; ZFPM2; HDAC5; NR2F6; POU2AF1; GATA6; PATZ1; PBX3; E2F8; SOX18; SMAD4; NKX2-1; EHMT2; ZNF529; ARID3A; PHOX2A; E2F3; CHD3; HDAC9; MYT1; ELF3; HEY2; SMAD7; BANP; IRX5; ZNF281; ACTL6B; EN1; LMCD1; ZNF232; SUMO1; MEIS2; NR4A2; SOX11; THAP11; SMAD1; ZNF415; YEATS2; PRRX1; ZNF304; NR4A3; SPIB; PCGF2; CREBL2; ZNF532; NEUROD1; MEOX1; TRPS1; HMGN3; RSF1; CITED2; ISL1; TCF7L1; CEBPA; ARL2BP; ZNF512B; CHD7; TFAP2C; IRF8; HDGF; NPAT; GFI1; EGR2; SAP30; ZNF331; TOB1; VDR; URI1; MAGED1; ID1; JUND; LEF1; ZEB2; ERBB4; ZNF423; CD3D; TWIST1; TRIM29; HOXC6