Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16505 Barasertib-hqpa GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 54 JUNB; IKZF1; RUNX3; ID2; TCEB2; BRD4; RBBP7; CTR9; KAT2B; ZBTB38; IRF1; SUB1; SATB1; BCOR; TRIM16; FOXD1; HLTF; LITAF; STAT5A; SERTAD2; YWHAB; TOB1; HTATIP2; RORA; CITED2; KDM5D; HHEX; BHLHE40; MTF2; PIR; SIX2; PRKDC; SOX10; STAT4; BMI1; KLF2; MAZ; CD3D; DNMT3B; FLNA; TXNIP; HLF; ZFP36L2; MAGED1; HOXA5; EGR3; RLF; JARID2; THAP11; NRIP1; STAT1; BCL11B; HOXB2; NR1D2
Down-regulation 103 SETD2; NR3C1; SUZ12; HOXB13; DACH1; GCM1; BRIP1; PAWR; CTBP2; BRCA2; BCL6; ANKRD1; TCF7L2; BTAF1; OSR2; ZNF444; TAF5; ZNF33B; ZNF22; TBL1X; REPIN1; RB1; CDK2; SND1; ZNF692; ZNF516; AR; E2F8; NKX2-1; ESR1; TRPS1; WNT4; RXRA; WT1; TCF12; ERBB4; TOPORS; ZNF180; EMX1; SALL2; HOXD10; EPAS1; BANP; TFEC; TFEB; ZNF467; FOSL2; ZSCAN16; FLI1; UIMC1; ISL1; CUX1; ZNF589; RBBP8; PBX3; ZNF124; EZH2; PSIP1; TULP3; ZBTB16; EMX2; HOXD11; ZBTB43; NR1H2; NR2F1; NCOA3; ARID5B; OVOL1; SMAD2; ZNF83; SUMO1; ZEB1; GATA2; KLF6; SAP18; SMARCC2; APEX1; ZNF350; SPIB; SSBP2; FOXG1; PIAS1; ZNF189; ZNF302; PGR; LMCD1; ZNF423; MXI1; ZFPM2; REL; ZNF91; TBX3; RBFOX2; ZNF443; ZNF85; IRF6; MEIS2; RBPJ; FOXJ3; TBX2; MAFB; TLE1; BHLHE41