Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16503 Vemurafenib GSE70138 MCF10A Human 3h 0.12uM EID0007
Types Number Response transcription factors
Up-regulation 75 KLF10; ESRRG; PPARG; RBPMS; BCL3; CEBPZ; MEF2C; HLTF; DRAP1; CHD4; ZNF580; EMX2; KAT2B; NCOA6; EYA2; DACH1; TGFB1; RBBP4; RBBP7; FOXJ1; ZBTB38; NR2F1; ESR1; HEY1; NR1D2; NUP62; ZNF532; CREB3; HDGF; ACTL6B; RBBP8; NFKBIB; CRYM; MBD2; FOXG1; MTDH; ERBB4; SMARCB1; TRIM28; MEIS2; ELF3; KLF6; NR4A2; TGFB1I1; PTRF; MYT1L; BIRC2; SOX17; ARL2BP; CARM1; PSIP1; TERF2; KLF11; VEZF1; ID3; SSBP3; SPEN; SMAD7; SALL1; PEG3; PTTG1; MTA1; FOSB; ZNF423; ATF4; ZFPM2; FOXF2; HES1; BHLHE41; ZIC1; MSX1; KDM5D; ID2; BMI1; RFX5
Down-regulation 121 ZNF410; MEOX1; BRCA2; BRIP1; CERS6; PAWR; CEBPB; HOXA1; CREB5; FOXO1; ETV4; TCEB2; ATF1; KLF4; ELF1; L3MBTL1; DDIT3; MNDA; LITAF; RBBP5; RCOR1; PQBP1; ZNF263; ZNF304; ETS2; SP110; NCOA4; WWP1; SOX9; ZNF587; FOXA1; ZNF257; ZNF140; IKBKAP; ZBTB11; GTF3A; PLAG1; ZBED1; ASCL1; HHEX; SMAD1; CERS4; GATA6; NANOG; LEF1; PSPC1; NRBF2; PSMC3; ZNF107; ZNF141; YAP1; NKX2-2; CREBL2; MEOX2; ZKSCAN1; EGR3; ZNF273; ZNF91; TRIM16; BCL11B; ZNF573; ZNF281; ZNF217; SOX11; CEBPG; ATF3; SSX1; TRIB3; SMAD2; SAP18; BHLHE40; PRRX2; TXNIP; ATF5; RNF6; ZNF200; AFF1; CCNC; NPAS2; CDK8; IRF9; IRF7; SATB2; JARID2; PHF20; TULP4; GLI2; ZFHX4; TDRD3; ZNF467; IRF8; JUND; GATA3; FOXO3; RORA; TSC22D2; TP63; STAT3; PBX3; ZNF551; IFI16; MAGED1; ZNF426; ARID5B; ZNF264; DNMT3B; ZNF93; ARNTL2; TLE1; HLF; HIRA; HOXC6; TRIM29; MAF; TOX3; ZNF430; ZNF43; HOXA5; MAFB; ZNF652; IKZF1