Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16502	Vemurafenib	GSE70138	MCF10A	Human	3h	0.37uM	EID0007

Response Information :

Types	Number	Response transcription factors
Up-regulation	100	EGR1; BATF3; SSBP2; TXNIP; ZIC1; NCOA6; ZNF160; NAB1; MAFG; TRIP6; BRD4; ZBTB38; ZNF721; SOX4; TRIM28; EGR3; DLX5; HOXB7; HEY1; ZNF337; CNBP; HMBOX1; MAFF; NFAT5; ETS2; PURA; SMARCA1; SNW1; EHF; RBM39; HLTF; DDX17; ZNF266; ITGB3BP; RERE; BBX; XBP1; CUX1; ZNF587; PBRM1; PRRX1; ERBB2; HOXA1; PLAGL2; CENPF; EPAS1; KDM5B; TBL1X; IRF4; PTTG1; MSX1; SHOX2; KLF7; FOXN3; NKX2-2; ZNF211; CHD7; COPS2; MTF2; EYA2; FOXD1; NPM1; TWIST1; ZNF593; HOXB2; FOXO3; SIM2; ELF3; CD3D; KAT6B; KLF9; YWHAB; ZNF331; PEG3; SPEN; HOXB6; DMTF1; CTBP2; ST18; ZEB1; ZKSCAN1; IRF7; SAP30; KLF5; IKBKAP; HOXB5; INSR; HDGF; ASCL1; ESR1; AEBP1; TCF7; EGR2; TRIM29; SNAI2; MXI1; HOXC6; NR2F6; TRIB3; ZNF91
Down-regulation	107	ELK3; ERF; BIRC2; ZMIZ1; GATA6; SMAD7; PIAS2; CAPN15; NRIP1; SUV39H2; MLLT10; CITED2; TEAD4; RCOR1; PPARGC1A; RARA; ZIC3; TRIM33; ARL2BP; DLX2; SAP130; RNF138; HOXB13; UBE2I; E4F1; BCOR; ADNP2; HINFP; ZFP69B; ZNF155; ID3; TCF7L1; MEOX2; TCF21; MED14; CNOT1; MYBL1; ELF2; ZNF34; TGIF1; FOXF1; HIVEP1; TTF2; THAP11; PIAS4; STAT6; TBX3; SOX18; ZSCAN31; LIN28A; HHEX; FLNA; CERS4; ARID4B; SMAD4; ISL1; ZNF623; FOXO4; MNAT1; ID1; ZNF682; NKX2-1; PBX3; LITAF; YAP1; ZNF12; ZNF423; NFIB; FOSL2; ZNF532; SMAD6; TGFB1; ZHX2; HIPK1; ADRB2; ZMYM2; REST; THAP10; HMGB2; TAF10; LOXL2; WWTR1; HIRA; CBFB; MEOX1; TOX; GLI2; ERBB4; CARHSP1; MBD2; MAGED1; CEBPA; GTF3A; ZNF267; HMGN3; ZFPM2; ZBED2; ZNF467; PGR; CALR; MEIS1; TLE4; DNMT3B; TDRD3; ID2; IRF8; TRIM22