Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16501 Vemurafenib GSE70138 MCF10A Human 3h 3.33uM EID0007
Types Number Response transcription factors
Up-regulation 479 TXNIP; NR3C1; ZBTB38; ADNP; ZNF586; IRF4; TBL1XR1; BATF; CEBPZ; ZNF587; WWP1; TFE3; ZNF408; STAT2; EYA2; PRMT2; NFIL3; DLX5; KAT2B; NCOA2; IRF9; BCL3; TERF1; ZNF304; ZNF160; ZNF211; CREBL2; ZNF124; TEAD1; BHLHE40; FOXI1; PPARGC1A; RARA; ZNF175; EP300; ZNF217; NR1H2; TRPS1; MYOG; MTA2; LHX2; MED23; MYCN; NKX2-8; CDK2; SMARCA1; SAP130; ZMYND8; TRRAP; CBFA2T3; SATB2; YY1; ELK4; PRPF6; REPIN1; TAF4; HDAC6; ZNF227; WNT4; HIVEP2; MDM2; HR; EGR1; ZNF611; ING2; CTR9; NR3C2; BCL11A; LITAF; KLF3; BARX2; ZNF419; EZH1; GLI1; RBM39; SPDEF; NFE2L3; HSF4; IL16; GATA3; TCEA2; BRF2; ERCC2; SSX1; NLK; NCOA1; TBX1; PRDM1; SKI; NFATC1; TRIP11; EVX1; HOXC10; WDHD1; ZNF721; LYL1; ZBTB16; RERE; NAB1; JAK2; CUX1; GLI3; ING1; MED25; KLF9; ZBTB1; KDM5B; PBX2; TAL1; MZF1; FLI1; ATOH1; KAT7; YEATS2; YBX2; KAT2A; FOXL2; ESR2; SMARCA2; ZNF253; ZNF226; NCOA3; KAT6A; THRAP3; JUN; PML; EBF2; POU2F2; CIITA; NSD1; ZNF556; TRIM32; KLF10; PRRX1; NFE2L1; KLF4; HDAC11; RUNX2; ESR1; ESRRG; TAF1C; LZTR1; KLF1; CREB3L2; SMAD6; NFX1; MAF; BCOR; HEY2; ITGB3BP; VGLL1; PEX2; ZNF263; SETD3; ZKSCAN7; BNC2; RBBP5; NFAT5; PRDM13; ZNF331; HLTF; IKZF4; LHX6; PEG3; SALL1; NHLH1; POU2F1; ZNF276; PITX3; BLZF1; DNMT1; ZHX3; PKNOX1; SSX3; FOXP3; ZBTB39; NFKB2; ZNF134; RARB; SP1; ZNF580; CDK8; IRF5; ZNF512B; MSX1; ZNF107; RUVBL2; LMO1; MAFG; PAX8; ZKSCAN5; SMARCA5; MYF6; MED16; PNRC1; ZNF688; ZBTB7B; PPP1R13L; PAWR; ID4; ZKSCAN4; JARID2; TRIM16; ARHGAP35; EED; BTG1; ASH1L; SAFB; KLF15; SP110; NFKBIB; HOXA1; NFE2L2; ZNF292; SSBP3; ZNF443; PIAS2; ALX4; ZNF91; ETV3; IRF2; STAT3; BACH1; TAF6L; ATF7IP; ZNF235; GTF2A1; LIMD1; VDR; EHMT2; NEUROD2; ZNF14; MBD4; RHOA; BCL10; ZNF783; ZNF84; ZNF562; TAF7L; PLAG1; MEF2C; ZFHX2; NPAS1; ZNF507; NKX2-5; RFX2; RCOR3; CBX2; NEUROG1; HDAC5; ZNF667; NEUROD4; ZNF711; TAF5; POU6F1; ZNF362; ZNF215; ZNF589; RBM14; TULP1; SUPT6H; SOHLH2; ZNF665; APBB1; SREBF1; SOX18; SCMH1; PREB; DLX4; ZNF236; RFX1; ZNF467; ASXL1; AFF1; ZNF473; LHX1; ZNF696; MXD4; ZNF287; IKZF1; SHOX; DNMT3B; FOXH1; POU4F1; ZNF444; SOX21; RXRB; LEF1; HOXA3; ZEB1; NAB2; FOXO4; BAZ2A; SOX12; SP3; PAX1; GTF2I; IRF7; MED17; ZNF629; TRIM33; DYRK1B; SOX17; ZSCAN32; ZNF710; NCOA6; ZBTB44; CRTC1; BHLHE41; ZNF93; BRD2; ZNF212; ATF6; AFF2; RSF1; VENTX; TULP4; E4F1; ZNF671; TLE2; ZNF225; PLAGL1; MED14; HMG20A; ZNF778; ZNF324; SUV39H1; RRN3; ZBTB32; PIAS3; L3MBTL1; TFCP2; FOXN3; ZKSCAN1; ZIC1; ZNF264; SCAI; ZNF274; ZNF544; LHX3; MYOD1; NR4A2; HIF3A; TFEB; CSDC2; ZNF345; TGIF2; HOXC8; ZNF222; SNAI1; CBX4; MNAT1; NPAT; NFIX; THRB; ZNF8; ZSCAN9; IRX5; ZNF329; HSBP1; ZBTB25; IFNB1; OVOL1; FOXC1; E2F8; ZNF574; JUP; ZNF506; ZNF669; ASH2L; ZNF83; ZNF768; TRIM27; ZNF394; SPIB; MSC; SIX1; ZNF652; ZXDC; CCNE1; PBXIP1; ZFP64; ZBTB43; TOPORS; CREBZF; ZNF764; ZNF510; CREB5; ZNF701; KDM5D; YEATS4; ZNF551; MED12; MLXIP; ZNF268; ZNF224; EGR3; NKX2-2; CNOT3; ETV6; SSBP2; NR2F2; ARNTL2; ACTL6A; ZNF45; OLIG2; RUNX3; ZNF606; ZEB2; ZNF516; ZNF44; PGR; GFI1B; HLF; TSC22D1; ZNF223; TAF1; SP140; TCF4; BCL6; ID2; ZSCAN16; BLM; SMAD7; PBX1; KLF7; CREB3L1; MXD1; RELB; CALCOCO1; MNDA; AEBP1; SIAH2; MEF2A; TFEC; PSPC1; MEOX1; MECP2; RBL2; CBX6; ZSCAN31; HES1; FOXE1; WWC1; SOX10; REL; SOX9; ERBB4; TGFB1I1; LPIN2; PHF20; HEY1; MYB; ZNF184; FOXD1; ELF5; ZNF136; TFAP2C; GTF2F1; MYT1L; NEUROD1; HMGB3; TRIM22; FOSB; FOXK2; NRIP1; PDLIM1; IFI16; KLF2; MAFB; GATA2; TSC22D2; HOXC6; FOXJ3; CRK; DBP; RBPJ; HOXB2; TBX3
Down-regulation 208 PSMD9; PCBD1; SMARCC1; PBX3; PUF60; ABT1; BIRC2; ILF2; CTBP1; RNF4; CNBP; E2F3; PMS1; TAF5L; CBX3; MTF2; MTDH; RNF138; DEK; PPRC1; YBX3; CEBPB; EGR4; DLX2; TFAM; MYCBP; TCF21; SUMO1; ENY2; HDAC3; ETS2; ATF4; BTF3; NKX2-1; HMGXB4; FLNA; SF1; MTF1; MEIS1; FOXF2; CALR; GTF2IRD1; MNT; HOXD11; PMF1; CTBP2; LOXL2; CDC5L; ELF1; CSDE1; CCNC; MED27; NEDD8; MLLT10; CCNA2; SRF; CAPN15; ZFP36L2; FOSL1; HMGN3; NUP62; XRCC6; ID1; PCGF3; STAT6; THAP4; YAF2; BAZ1A; ZNF410; CCDC59; PITX1; POLR2A; ATF3; ECD; FUBP1; ESRRA; BRIP1; CEBPD; AIP; TEAD4; SP100; C1D; RXRG; COPS2; ABL1; FOXA1; HSF2; PSIP1; UBE2I; PSMC3IP; MED20; HOXB6; ANKRD1; LIN28A; MYBL2; MED1; HAND1; COPS5; DR1; FOXM1; NR1I2; TGFB1; RAN; ZZZ3; NPM1; C1QBP; SFPQ; POLR3C; SOX11; ZNF32; SHOX2; PAX6; CHD7; TAF1A; CARM1; RBFOX2; CENPB; CITED2; NCOR2; TEAD3; GMNN; VPS72; RBBP7; CEBPG; SMARCE1; USP16; KLF5; BRD4; APEX1; SUZ12; CNOT1; ZNF423; SIX2; ATF1; TAF1D; EZH2; SSRP1; PA2G4; TTF2; FHL2; TCF25; ZNF593; SMARCD2; MEIS2; ZNF239; NCOA4; HMGA1; ASCL1; FOXN2; BRD7; ISL1; NR4A3; VGLL4; TAF9B; HDGF; YAP1; MED24; RFX5; MYC; CERS4; NKX3-1; TBP; ATN1; TCERG1; TRIM29; HIRA; ETV1; GTF3A; ZFHX4; TDP2; HHEX; HIF1A; NANOG; KLF6; PRKDC; ZFPM2; SALL2; TFAP2A; CENPF; NFKBIA; HOXA5; CHD8; USP22; TLE4; URI1; EGR2; CBFB; SMARCB1; RUNX1; IKBKAP; RNF6; MAGED1; TCF7L1; HNRNPD; MECOM; GTF2A2; ERBB2; RBBP8; ARNT2; ZNF43; ID3; IRF6; TFDP2; INSM1; HOXD1; HOXB7; SNAI2; NR2F6