Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16500 Vemurafenib GSE70138 MCF10A Human 3h 10uM EID0007
Types Number Response transcription factors
Up-regulation 59 TSC22D3; PCGF3; EMX2; NR0B2; TEAD1; KDM5B; XBP1; OSR2; ZMYND8; ESR1; GLI3; BNC2; TCF12; PEG3; ZMIZ1; POU2AF1; ZFPM2; TFAP2C; ZNF331; SOX2; ZNF217; SMAD1; GATA6; NEUROD1; CREM; KLF4; MITF; ZNF83; KLF11; AEBP1; HOXB2; LOXL2; TWIST1; MEIS2; ADRB2; AHR; RBFOX2; TOX3; PBX1; RORA; RBBP8; SPIB; MEIS1; PAX5; NR4A3; HOXB6; MYRF; TRIB3; VPS72; HOXB5; TCF4; WT1; SATB1; HOXA5; EGR2; IRF6; NR2F6; HOXD1; SNAI2
Down-regulation 35 PUF60; HMGA2; MED1; PATZ1; KAT6B; EZH2; HEY1; RNF6; ELF5; ADNP2; BRD2; HOXC10; MTF2; ZBTB16; RUNX3; ARID4B; SPEN; NKX3-1; CD3D; ZNF32; SALL1; LEF1; MXI1; FOXC1; MYB; BMI1; HOXC6; ABL1; MTA1; FOXJ3; ZBTB18; HOXA10; ID1; RFX5; MSX1