Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16484 Geldanamycin GSE70138 MCF10A Human 24h 0.04uM EID0006
Types Number Response transcription factors
Up-regulation 436 HBP1; PBXIP1; CALCOCO1; FOXO4; ZNF117; ZNF91; PRDM2; ZKSCAN4; IRF9; PNRC1; HDAC5; ZNF219; NR3C1; NCOA2; CSDC2; CREBL2; FOXN3; TBX21; ING4; ZSCAN18; SIX6; HOXB1; GBX1; SALL2; CIR1; KLF13; SPI1; HOXA4; LHX3; ZNF665; ARRB1; ZNF224; GLI2; ZNF331; DYRK1B; ZNF175; ZNF223; CBX4; ZNF85; NR5A1; CHD2; RARG; ERBB4; RORC; BARX1; MNT; RAX; PRDM14; ZNF688; PDX1; JUP; BPTF; STAT2; ZNF205; TULP2; CDIP1; FOXN1; PAX6; BRWD1; ZKSCAN3; TP73; ZNF43; DBP; ALX3; GCM1; ZNF74; ETV6; ZNF362; ZNF500; CBFA2T2; BNC2; VENTX; SRCAP; RARB; TRIP11; EMX1; ZNF415; CRX; POU3F2; GON4L; NEUROG1; HIF3A; ZBTB44; HMBOX1; TCEA2; TFAP2A; MYOG; IRF6; EZH1; SOX21; HSF4; ZNF446; SUPT7L; ZMIZ1; ZNF221; NFATC3; ZNF83; SCRT1; CBX7; CCNT1; ZNF93; NEUROG3; ZNF778; RXRG; ZNF345; TBX4; PHF1; KLF3; ZNF682; ZNF141; ZNF606; ZNF44; ZNF154; SOX18; DDIT3; NCOA3; ETV2; MZF1; ZNF671; TEAD3; HOXB5; THRA; HOXA5; AES; OVOL1; ZNF667; ZNF174; SIRT2; TSHZ2; THRB; GRIP1; TRIM22; HOXD1; MEF2D; FOXB1; MED12; ZBTB3; ERBB2; MAML3; ZNF33B; ZNF701; ETV7; PRDM10; ZNF536; GFI1B; MEOX2; CRTC1; PITX3; INSR; ZNF165; HMX1; MYF5; ID4; ZNF768; HOXD3; NFIX; TEF; SETDB1; TLX3; ZNF669; RSF1; TULP1; IKZF2; TSC22D4; BAZ2B; HEYL; ZNF358; CBX2; VGLL1; DLX4; ZHX2; ATF3; ALX4; FOXD3; SRY; PPARA; SOX13; ZNF264; HINFP; PDLIM1; TBX19; NHLH1; ARHGAP35; POU4F3; ARID5B; ZNF549; ZNF695; GLI3; JUND; HOXD13; POU3F4; PRDM12; RXRA; ETV3; ZNF654; ZNF675; YBX2; ZNF304; SIX3; GRHL2; ZNF350; ZNF214; TCF7L1; HMG20B; NHLH2; ZNF354A; ZNF136; POU3F3; RXRB; ELF4; TRAK1; IRF7; ZNF253; HESX1; AFF3; WNT4; SOX3; EVX1; TCF15; ZNF816; NFATC1; RFX1; IFNB1; NR1H2; HOXB8; ARID5A; MEIS2; BCL11A; ZNF132; HOXA2; HLX; ZNF225; NFATC4; KDM4C; ATOH1; CARF; ZNF133; ST18; ZNF34; NR5A2; POU1F1; HOXB3; APBB1; DCC; E4F1; ZNF711; ZNF177; ZNF257; DMRT1; TP63; ZNF292; PBX1; GSC2; ZNF426; SOX2; AR; PIAS1; TBX10; HOXA3; FOXH1; TOX; SOX14; TLE2; LMO1; ATF7IP; EPAS1; ATF4; IRX4; MED25; TSC22D3; ZSCAN16; POU6F2; VPS72; ZKSCAN1; TLE4; ZNF112; GBX2; PAX9; SOX5; GATA1; HOXB2; MAF; ZNF611; ZNF155; L3MBTL1; FLI1; HIC1; ZNF81; BCL6; NEUROG2; TXNIP; SOX4; ZNF135; ZNF423; HEY1; ELF5; KDM5C; ZSCAN9; ZNF75D; KAT2B; NAB2; JAK2; ZKSCAN8; MLXIPL; ONECUT2; CERS4; RING1; TFDP2; TBX5; HOXA6; ZNF254; ZNF589; ZNF623; OVOL2; ZFPM2; HR; POU2F1; FEZF2; TRPS1; INSM1; REL; IL16; PIAS4; ZSCAN31; CEBPD; MYCL; ZNF573; STAT4; HOXC8; LITAF; NR1H4; TBX1; TCF25; EHMT2; KDM5B; IKZF3; NKX2-2; PKNOX2; MSC; ZNF394; ZNF148; MXI1; MDM2; SCAI; TRIM29; PHIP; MAFF; LHX2; CREM; MEF2C; KLF11; RBPJ; ZNF268; TULP4; SMARCC2; TFAP2C; HDAC9; RYBP; BTG1; NR4A2; SOX17; EYA1; TULP3; SOX10; SHOX2; ARID4B; ZNF430; TGIF1; MYRF; MEOX1; NR4A1; LYL1; CUX2; ARNT2; FOXA1; AEBP1; ARID3B; BBX; MECP2; GATA6; CRYM; NCOA1; SSBP2; CHD9; IRF1; CBFA2T3; TCF4; ZNF12; HIC2; FOXG1; ZIC3; MKL2; DLX5; PEG3; ZMYND8; SOHLH2; ZBTB20; ZNF160; KLF7; NR4A3; BRD4; TERF1; MXD4; ZIC1; SMAD6; NPAS2; NR1H3; NEUROD1; SOX11; CEBPA; KLF5; TFEC; BHLHE41; TRIB3; RORA; SMARCA1; FOXF1; EHF; OSR2; TAL1; MED13; PBX3; NFE2; SP140L; IRF8; PITX2; FOXO1; ZNF652; ASCL1; ZEB2; DACH1; TOX3; TBX3; CREG1; GATA3; FOS
Down-regulation 117 FOSL1; TFDP1; HMGA2; MYC; EZH2; EGR1; RUVBL1; PUF60; TCERG1; MYCBP; RUVBL2; FHL2; TBP; NUP62; HSF2; CBFB; BRCA1; DRAP1; ITGB3BP; PPRC1; SSRP1; PA2G4; MYBL2; XBP1; CCNA2; GTF2A2; PARP1; SF1; TBPL1; EDF1; HNRNPD; BAZ1A; UBP1; SFPQ; HLTF; NOC2L; EED; RBM14; ORC2; CHAF1B; DR1; ETV1; RAN; DNAJC2; WDR77; RNF138; C1QBP; PSMC3IP; NPM1; GMNN; PLAGL2; ELK3; TAF1D; CCDC59; ADRB2; GABPB1; BMI1; ZBTB18; CTNNB1; FOXM1; WDHD1; NELFB; KMT5A; LEF1; NFIL3; ZNF593; TRIM28; BAZ1B; ZNF146; TEAD4; PRKDC; SAP30; MTDH; HMGA1; PTTG1; MLX; MED6; ING2; EGR3; YWHAB; RBBP8; HMGB1; BCLAF1; YBX1; SUB1; PTRF; FLNA; HOXC6; BIRC2; CEBPZ; TSC22D2; ENO1; ECD; CHD7; ETS2; TRIM32; CALR; HDAC1; HMGB2; ELF1; ID1; GTF3A; RNF6; HSBP1; CTR9; RBBP4; MYB; CENPF; JARID2; HMGB3; SNAI2; SATB2; MNAT1; NR2F2; PITX1; SUV39H1; NKX3-1