Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16483 Geldanamycin GSE70138 MCF10A Human 24h 0.12uM EID0006
Types Number Response transcription factors
Up-regulation 393 CALCOCO1; FOXO4; HBP1; NR3C1; PBXIP1; ZKSCAN4; ZNF91; ZNF117; PNRC1; PRDM2; PHF1; MZF1; IRF9; DYRK1B; ZNF219; NCOA2; CREBL2; ELF4; ZNF224; KDM5A; ZNF446; HOXA4; ZNF665; ZBTB44; STAT2; MNT; ZNF345; ZNF223; CIR1; ZNF83; ZSCAN18; SALL2; ZNF362; HMBOX1; TRIM22; ING4; OVOL2; ZNF536; SIX6; NR5A1; NFATC3; ZKSCAN3; GLI2; BRWD1; CHD2; ST18; RARG; ZNF415; GBX1; BPTF; RORC; CRX; CBFA2T2; ZNF667; ZMIZ1; ZNF175; SMARCC2; ZNF444; ZNF350; SPI1; RBL2; ZNF85; EZH1; TULP2; L3MBTL1; BAZ2A; POU3F2; IRF6; ZXDB; PRDM14; TRAK1; CDIP1; YBX2; ZNF154; CSDC2; PPARA; SUPT7L; TFAP2A; HIF3A; HOXB5; ZNF33B; ZNF304; HOXB3; CBX7; ZNF471; LZTR1; ZNF711; TCEA2; GRHL2; VENTX; HOXB1; KLF3; KLF13; HOXA5; RXRG; ZNF500; NFATC4; ZNF135; ERBB4; LHX3; ZNF331; THRB; CARF; ZNF44; FOXN3; INSR; ESR2; HINFP; ZNF606; TBX4; ERBB2; PBX1; ZNF214; TCF15; ZNF141; MAML3; IRF1; TBX21; ZBTB3; ETV3; ZNF133; TSHZ2; NR2C1; ZNF354A; ETV6; HOXB13; AR; BAZ2B; EPAS1; ZBTB7A; SCRT1; BCL6; RXRB; PAX6; RSF1; HOXD3; JUP; DBP; TFAP2C; MED12; NFIX; NHLH2; ZIM2; AFF3; TP73; ZNF165; HDAC5; TLE4; APBB1; ZNF688; ZNF682; ZNF264; KDM5B; SETDB1; ZNF550; SOX3; TSC22D3; ZNF701; ZNF286A; RBPJL; ZNF222; TEF; ZKSCAN8; HSF4; GRIP1; DDIT3; BARX1; ZNF358; ZNF177; ZNF669; ZNF611; SRY; RARB; MXD3; TBX19; ZNF155; JUND; PDLIM1; BCL11A; ZNF334; ZBTB20; TULP1; FEZF2; EMX1; SOX2; ZNF675; CEBPA; ZNF43; HMG20B; PRDM9; HNF4G; SOX18; GCM1; ZSCAN31; ZNF112; HOXA3; IRF7; ZKSCAN1; NCOA3; POU1F1; MSX2; TLX3; ZNF132; NR1D2; ZNF225; BTG1; ZNF573; RXRA; MYF5; SOX21; ZNF671; ZNF467; ZNF623; NHLH1; ZNF510; ZNF257; AFF2; BRDT; DCC; ZNF254; TRIM29; NAB2; NR5A2; HMX1; IKZF3; PKNOX2; MBD4; HESX1; ZNF12; CIITA; MEOX2; GSC2; MYRF; TBX5; ATF3; CITED2; TRPS1; RFX3; ZIC3; ZNF253; RFX7; ID4; MEOX1; BBX; EHMT2; ZNF287; ZNF80; PEG3; MECP2; TGIF2; ZNF148; WNT4; BHLHE41; HOXD1; THRA; SCAI; ZNF93; SIM1; TULP3; BNC2; FLI1; SIRT2; TFDP2; MLLT10; TP63; LITAF; ZNF268; SMARCA1; TOX; MNDA; POU6F2; ZNF329; FOXA1; TCF4; KLF11; MYCL; ZNF587; TCF25; BRD4; HOXB2; MLXIPL; KMT2A; ZNF674; AES; USP21; ZNF157; POU2F1; ATOH1; ZNF160; ZNF544; ZMYND8; NR1H2; ZNF580; SUPT3H; MDM4; MED14; NFAT5; DLX4; ZNF419; ZNF136; VPS72; SOX5; ZNF423; TLE2; TCF7L2; CBFA2T3; NR1H4; NKX2-2; INSM1; ZNF432; ATF7IP; TERF1; SIX3; BCL3; CHD4; MXD4; PHIP; HEY1; NFE2L1; ELF3; TFEC; HOXB6; MXI1; MKL2; FOXF2; MEIS2; NR0B1; SOX13; DMTF1; ETS1; SREBF1; TCF7L1; TBX1; MAF; EP300; OSR2; ARNT2; TXNIP; KDM5C; SMARCD3; SP2; ZNF394; PFDN5; CHD9; LIN28A; EN1; STAT4; NR1I2; CDX1; ZHX2; NEUROD1; SOX17; MED13; TBX3; ARID5B; GATA6; NR1H3; EBF2; ZNF721; ZFHX4; HLX; MEIS1; TBL1X; PBX3; ZNF589; SSBP2; CERS4; KAT2B; ZNF512B; KLF5; KLF4; HDAC9; CUX2; MYCN; SPDEF; WT1; TOB1; TCF7; SMAD6; FOXF1; TWIST1; CREB3L2; ZNF652; TRIB3; SPIB; CREB1; NR2F6; MECOM; ESR1; GATA3; BASP1; FOS; IKZF1
Down-regulation 117 FOSL1; HMGA2; MYC; RUVBL1; EZH2; PUF60; EGR1; TFDP1; FHL2; TBP; CBFB; SUB1; GTF2A2; HSF2; RUVBL2; NFIL3; ELK3; DRAP1; MYBL2; MYCBP; TCERG1; NOC2L; CDK2; PREB; HDAC2; CHAF1B; ITGB3BP; NUP62; PPRC1; PSMC3IP; RBM14; DDX54; EGR3; SSRP1; SMARCA4; BRCA1; PA2G4; CCNA2; WDR77; C1QBP; ZNF146; PARP1; MYBBP1A; GMNN; ARNTL2; RNF138; HMGA1; GABPB1; MED6; TSC22D2; BAZ1A; BLM; ETV1; EED; CALR; TBPL1; HMGB1; DNAJC2; LEF1; HNRNPD; XBP1; UBP1; CCDC59; BCLAF1; ADRB2; NFKBIA; RNF6; BAZ1B; ENO1; EDF1; MLX; TRIM32; CEBPZ; SFPQ; RAN; CRY1; SF1; GTF3A; GCFC2; FOXM1; ZBTB18; ZNF593; NFKB1; YWHAB; ING3; JUNB; BMI1; TRIM28; ZNF267; CTNNB1; SATB2; PTTG1; NPM1; CDK8; HOXA11; JARID2; TEAD4; VDR; CHD7; HES1; BATF3; FOXD1; KLF2; ELF1; ECD; MYB; HOXC6; THAP11; GATAD2A; ETS2; SMAD7; ZFP36L2; SMAD1; NR2F2; MSX1; SUV39H1; IKBKAP