Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16482 Geldanamycin GSE70138 MCF10A Human 24h 0.37uM EID0006
Types Number Response transcription factors
Up-regulation 398 CALCOCO1; PBXIP1; HBP1; FOXO4; NR3C1; IRF9; PRDM2; ZNF117; ZNF91; ZNF446; ZNF224; HMG20B; ZKSCAN4; PNRC1; ZNF223; HDAC5; HOXB5; IRF6; ZNF571; BPTF; GRHL2; ING4; ZBTB44; ZNF536; TBX21; SALL2; MZF1; ERBB4; PHF1; ZNF665; ZNF175; ZNF83; ZNF345; ZNF606; CBX7; ZNF85; GBX1; RORC; OVOL2; CREBL2; HOXA4; AR; NR5A1; CSDC2; SIX6; CHD2; DYRK1B; HOXB3; ZNF219; ZNF415; NCOA2; ZSCAN18; TSHZ2; THRB; HEY1; ZKSCAN3; CIR1; AES; ZNF76; ZKSCAN1; ZNF444; CBFA2T2; TLE4; ZNF44; MEOX2; HOXB1; HMBOX1; TEAD3; HIF3A; ZNF362; KLF13; HOXC11; TRIP11; STAT2; ZNF467; CRX; HOXB2; ZNF331; HOXB13; EZH1; ALX3; CEBPA; INSR; MYOG; CDIP1; RAX; FOXN3; ZNF264; TULP2; ZNF701; ZNF350; TCEA2; BAZ2B; ZNF205; MAML3; MEF2D; ZNF177; CITED1; ZNF667; FOXA1; ERBB2; ZNF112; APBB1; PPARA; TBX4; WNT4; RARB; TRIM22; THAP10; ZNF500; BARX1; HOXA5; HOXD13; ZNF136; GCM1; EMX1; IKZF2; BCL6; CCNT1; ZXDB; SETDB1; PBX1; AFF2; POU3F2; ZNF43; SRY; ZNF33B; HSF4; ZNF688; MNT; ZNF133; MEOX1; ZIM2; ARID5A; TCF25; ZMIZ1; SPI1; NR6A1; LHX3; RSF1; YBX2; ZNF611; ZNF155; ATF7IP; VENTX; ZNF214; ETV3; ZNF507; CRYM; ZNF471; ZNF74; SOX3; RXRB; ZNF816; OSR2; THRA; NFIX; ZNF506; PRDM14; MYCL; ZNF154; ZNF135; TCF4; ATOH1; ZNF682; POU2F3; NEUROD6; RXRG; ETV7; MYF5; ZNF675; ELF4; MBD4; HINFP; PAX6; ASCL3; SUPT7L; TFAP2C; ZNF141; RARG; ZBTB3; ZNF768; TP73; CARF; TCF15; ELF2; HMX1; BCL11A; MYRF; SIN3B; TBX10; SMARCC2; ZNF671; PDLIM1; TBX5; ZNF132; ZNF384; ZNF358; NFAT5; ZNF253; DBP; SIX3; HNF4G; ZNF394; MEIS2; GLI2; TP63; LZTR1; FOXB1; ARID5B; ARID1A; RING1; TRPS1; PRDM9; IKZF3; LITAF; PRDM12; MAZ; SCAI; HOXA6; HESX1; FEZF2; MED12; DCC; HOXD11; MEF2C; ID4; MED25; TCF12; ST18; MLXIPL; RERE; ZNF257; TXNIP; BAZ2A; ZNF304; ZNF81; RXRA; TULP1; ZFY; ARID4B; TLX3; TCF7L2; KDM4C; GFI1B; SPDEF; ZNF254; POU1F1; SIRT2; NFATC3; RFX3; ZSCAN16; ZNF225; NR1H2; ZNF334; ZNF93; KLF3; ZNF287; CERS4; TBX19; SOX2; HOXD1; L3MBTL1; HOXA3; ZSCAN31; PAX9; BNC2; MKL2; TCF7; NR0B1; DMRT1; TBX3; PHF8; ZNF711; FLI1; TRIM29; ZNF268; RBPJ; BANP; POU6F2; SOX18; MYCN; BHLHE41; ZHX2; ZKSCAN8; MDM4; TFCP2; NHLH2; SOX4; PKNOX2; ZNF80; KDM5A; ZNF407; MNDA; RORA; PIAS4; ZNF160; SOX5; ZNF12; HDAC9; LDB1; SHOX; PFDN5; BTG1; TSC22D3; EYA1; NKX2-2; ZNF140; SOX13; KAT2B; ZNF430; SP2; ZBTB20; TCF7L1; BCL3; CREB5; INSM1; ELF3; ZNF573; TLE2; USP21; GLI3; NR4A1; ZNF544; SIM1; NFATC4; ASCL1; ZMYND8; ZNF652; STAT4; ZNF432; JUP; DLX4; JUND; SIX2; NPAS2; FOXG1; NR1H4; ARNT2; BRD4; ZIC3; ZNF148; MAF; CUX2; NR5A2; GATA6; ELF5; OLIG2; EP300; CBFA2T3; TULP3; MXI1; CHD9; MXD4; SPEN; MEIS1; MED14; KDM5B; KLF5; HOXB6; ZNF423; SHOX2; HIC2; SOX17; EHF; ZEB1; PEG3; KLF11; TFEC; IRF8; PCGF2; TOX; DLX5; SOX10; VPS72; SOX9; HEY2; PHIP; PGR; SMARCD3; ATF3; TBL1X; CREB3L2; SALL1; ARID3A; TOX3; ZNF721; FOXF1; NCOA1; TRIB3; FOXA2; TWIST1; SSBP2; WT1; ESR1; GATA3; PBX3; MECOM
Down-regulation 107 FOSL1; TFDP1; HMGA2; MYC; EGR1; RUVBL1; PUF60; EZH2; TCERG1; RUVBL2; PPRC1; MYCBP; CBFB; NUP62; HNRNPD; MYBL2; TAF1A; ELK3; TBP; MYBBP1A; CHAF1B; CCNA2; GABPB1; PARP1; SSRP1; C1QBP; HSF2; PSMC3IP; RBM14; TSC22D2; PA2G4; SF1; ITGB3BP; BRCA1; DRAP1; TCFL5; WDR77; RNF138; NOC2L; EDF1; TBPL1; NFKBIA; CNBP; CHD1; DR1; NFIL3; RBL1; SFPQ; NPM1; BCLAF1; FOXM1; CEBPG; CTNNB1; KMT5A; XBP1; DNAJC2; YWHAB; EED; GCFC2; CBX3; HMGA1; BLM; MTDH; ENO1; RAN; SMARCA4; PTTG1; LEF1; BAZ1A; MLX; ORC2; TAF9; ADRB2; TFAM; PMS1; BATF3; ZBTB18; CCNC; CCDC59; VDR; EGR3; ZNF593; DDX5; CEBPZ; SNAI2; ZNF281; SAP30; BMI1; CENPF; HLTF; KLF2; CHD7; ID2; RBBP4; PQBP1; RNF14; HMGB2; ETS2; ID1; SMAD1; HES1; MAFB; HOXC6; MNAT1; SUV39H1; EGR2; ZFP36L1