Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16481 Geldanamycin GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 407 CALCOCO1; PBXIP1; FOXO4; HBP1; IRF9; ZNF117; SALL2; KLF13; CSDC2; HEY1; SIX6; PRDM2; ARRB1; ERBB4; ZKSCAN4; RARB; ZNF219; NCOA2; CBFA2T2; ALX3; DYRK1B; ZNF91; GBX1; HDAC5; HIF3A; NR3C1; CREBL2; HOXA4; GLI2; ZSCAN18; RORC; MYOG; HOXB1; ZNF500; ZNF76; HOXB13; PNRC1; NEUROG1; IRF6; ZNF536; SETDB1; PRDM14; CRX; CRTC1; LZTR1; ZNF688; EZH1; TFAP2A; TBX4; GRHL2; ZNF223; TBX21; ZNF224; HMG20B; ZNF446; TSHZ2; PDX1; INSR; BPTF; RAX; CDIP1; GLI1; ZNF141; NR5A1; LHX3; GFI1B; TRAK1; BARX1; SOX13; ZBTB44; THRB; ZNF154; ZNF665; ZNF345; BRWD1; STAT2; ZNF85; SRCAP; PHF1; HOXD1; ZMIZ1; CBX7; JUND; PBX1; HOXB5; ZNF33B; KLF1; GATA1; ZNF74; ST18; ZNF175; EMX1; CITED1; HINFP; TAF1C; DBP; ZKSCAN3; ZNF589; ZBTB7A; CHD2; OVOL2; APBB1; TBX10; NEUROG3; PAX6; ZNF415; TP73; ZBTB7B; NR5A2; ING4; AES; TCEA2; TCF15; ETV7; RARG; ZNF778; HMBOX1; NFATC3; ZNF362; HOXD13; SPI1; TRIP11; NPAS2; ZNF646; HSF4; MZF1; ID4; ATF3; IKZF4; VENTX; AFF2; ZNF606; MEF2D; RING1; RXRG; HOXA5; HOXB3; TFAP2C; PITX3; BCL11A; MBD1; SCRT1; RXRB; ERBB2; SUPT7L; IKZF2; MAF; NHLH1; ATOH1; ELF4; ETV3; NR1H2; TLE2; NFATC4; CIR1; ZNF205; TCF7L2; MED12; L3MBTL1; ZNF816; NRL; CRYM; TULP2; GRIP1; TEAD3; ZNF444; THRA; CBFA2T3; HOXB2; HMX1; ZNF768; RSF1; EVX1; MEOX2; ARID1A; NKX2-5; ARID5A; FOXB1; MED25; TBX19; ZNF711; PPARA; TCF7L1; KLF15; ZNF467; MEIS2; AFF3; VPS72; NCOA3; ZNF654; FOXN3; SOX18; TOX; ZNF669; PKNOX2; TEF; MYF5; ZNF286A; ZNF133; TLX3; SREBF2; ZNF264; ZNF358; DLX4; ZNF44; USP21; IRF7; NR0B2; ZNF423; POU3F2; FOXH1; SIRT2; CBX4; EYA1; SIX5; ZFHX2; ASCL3; RBPJL; PDLIM1; TULP1; ARHGAP35; SUPT5H; SMAD3; NR2C1; DCC; HOXD3; BAZ2B; SOX21; ZKSCAN1; IKZF3; SMARCC2; GLI3; NR4A1; MNT; LDB1; NAB2; MLXIPL; ZNF132; POU2F1; HOXD11; ARID5B; SOX2; NEUROD2; HDAC9; EPAS1; SIX3; GCM1; ETS1; ZNF83; KDM5B; ZNF112; ZNF350; ZSCAN31; PROP1; NFIX; SIN3B; ZSCAN9; EHMT2; KLF3; HEY2; MEOX1; TFCP2; ZNF214; TBX5; PIAS4; ARNT; HOXA2; CEBPA; ZNF135; ZSCAN16; FOXF2; NFE2L1; ARID3B; EP300; SP4; ZHX2; CITED2; MYCL; ZNF682; BCL6; SRY; ZKSCAN8; SPDEF; TRIM22; ATF7IP; TFDP2; ZNF225; TSG101; POU1F1; NR2F1; RFX3; ZNF671; MEF2C; SHOX2; ZNF235; ZNF43; TAL1; ZNF253; TRPS1; HOXA3; MXI1; ZIC3; RFX2; SMAD4; SOX3; SOX10; ZNF580; HNF4G; ZNF611; ZNF324; SOX5; POU6F2; KDM5C; ZNF334; ZBED1; ZNF155; TCF4; TLE4; FLI1; MYRF; FEZF2; ZNF75D; ELF3; ZNF93; ZNF257; IRF1; CERS4; CDX2; PBX2; RXRA; ZNF573; ZNF331; NHLH2; CARF; NFE2; KAT2B; AR; CUX2; WNT4; BACH2; HESX1; TSC22D3; ATN1; MKL2; POU2AF1; BNC2; MYCN; HOXC8; ZMYND8; TBX3; CUX1; JUP; TULP3; NCOA1; OSR2; RBPJ; TCF25; DEAF1; SMARCD3; ARID4B; KLF11; ZBTB20; DLX5; E2F8; PHIP; FOXA1; GATA6; TP63; STAT4; SSBP3; FOXA2; BRD4; HOXB6; ZNF512B; SP2; SMARCA1; DDIT3; CHD9; SIX1; TGFB1I1; MECP2; ARNT2; CSDE1; LITAF; ZNF544; ZEB1; TERF1; FOXF1; OLIG2; TXNIP; KLF4; TBX1; MED13; ELF5; ZIC1; TRIM29; ARID3A; SPEN; SOX17; NKX2-1; TRIB3; SSBP2; PEG3; CREB1; ZNF652; TOX3; MEIS1
Down-regulation 112 FOSL1; TFDP1; EGR1; HMGA2; MYC; FHL2; RUVBL1; EZH2; USP22; PUF60; MYCBP; TBP; TCERG1; RUVBL2; PPRC1; SSRP1; HSF2; ITGB3BP; PARP1; GABPB1; TSC22D2; BRCA1; DRAP1; SFPQ; PA2G4; TBPL1; MYBL2; C1QBP; CBFB; MED6; NUP62; SMARCC1; CCNA2; GTF2A2; EDF1; HOXC6; ELK3; BIRC2; CHAF1B; CEBPG; ENO1; FOXM1; YWHAB; DNAJC2; HMGA1; TRIM32; HNRNPD; TRIM28; CDK2; PSMC3IP; RAN; TRIM27; RBM14; ELF1; NFKB1; PTTG1; LEF1; RNF6; NPM1; XBP1; BMI1; CEBPZ; RNF4; ZNF473; EGR3; ZNF593; BCLAF1; PURA; EED; CCDC59; ORC2; DR1; ZNF146; SNAI2; ADRB2; SAP30; TFAM; NFIL3; TEAD4; HMGB1; FOXD1; CCNC; FLNA; BAZ1A; ING3; SMARCE1; VDR; CTNNB1; ID2; CRY1; ZBTB38; YBX1; GTF3A; DDX5; ERG; HES1; PQBP1; MTF2; ECD; SMARCA2; ETS2; NR2F2; GATAD2A; CENPF; ZBTB18; HLTF; KLF2; SCAND1; BRD2; MAFB; SUV39H1; ID1