Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16479 Geldanamycin GSE70138 MCF10A Human 24h 10uM EID0006
Types Number Response transcription factors
Up-regulation 568 CALCOCO1; HBP1; ZNF117; PBXIP1; ZNF91; PRDM2; HOXB1; ERBB4; ZKSCAN4; IRF9; ZNF85; CHD2; HOXB5; SIX6; KLF13; ZBTB44; CSDC2; TBX21; RORC; ZNF536; ZNF223; NCOA2; NR3C1; LHX3; GBX1; NR5A1; EMX1; SALL2; THRB; PRDM14; CBX7; ZNF415; HDAC5; TULP2; ZNF331; NFATC3; ZKSCAN3; ZNF665; ZNF154; AFF2; RARG; PAX6; VENTX; PNRC1; NEUROG3; ZNF682; CBFA2T2; ALX3; BRWD1; PAX1; ZNF224; ING4; BPTF; GCM1; ZNF345; SCRT1; FOXN1; ZNF701; TP73; THRA; HINFP; HOXA4; SRY; ZNF350; TDP2; HOXB13; ZNF362; SOX3; NEUROG1; FOXO4; ZNF43; MZF1; ST18; ZNF33B; ZNF44; TRIP11; ETV3; ZNF221; ZSCAN18; NFATC4; ASCL3; CREBL2; ETV2; PDX1; MEIS2; KLF1; MAML3; TFAP2A; ZNF219; ZNF177; CRX; PRDM12; ZNF654; PHF1; TBX4; FEZF2; AR; ONECUT1; ZNF571; ZNF174; PROP1; MXI1; PAX7; PITX3; ZSCAN16; IRF6; TEF; ZBTB3; ZNF175; SOX13; GRIP1; CIR1; ZNF471; HOXC11; PRDM9; HIF3A; ZNF778; ZNF75D; ZNF79; NEUROD2; ZNF500; NFIX; ZNF506; SOX21; ZNF669; RXRG; RORB; ZNF93; ZNF695; CRYM; PAX2; HOXD13; MAPK8IP1; ZNF195; SIN3B; ZNF304; ZNF549; SOX2; SOX18; ZNF222; ZNF671; SPI1; MBD4; HOXC5; MED12; FOXD3; HOXB6; EZH1; ZNF141; TLX3; DDIT3; SSX7; NHLH2; ZNF484; CBX4; POU3F4; TULP1; TFDP2; KLF15; ZIC3; ZNF74; ZNF675; DYRK1B; YBX2; ZNF507; HEY1; TSHZ2; AFF3; ZNF257; TAF1; KAT2B; FOXE3; FOXH1; TBR1; ZSCAN9; CRTC1; NCOA3; ZNF214; CBX2; GFI1B; NRL; ZNF41; FOXB1; RFX3; ZXDB; ZNF76; ZNF711; TFAP2C; ZNF446; NHLH1; APBB1; ZNF510; TBX5; HDAC9; NEUROD6; HOXB8; PRDM10; PAX3; HOXB2; ZNF10; ZNF550; POU4F3; ZNF254; ZNF235; NKX2-5; CARF; RAX; RARB; DCC; BARX1; ZNF253; ID4; GBX2; STAT2; CDX4; ZIC4; ZIM2; ARID5B; BCL11A; ZNF287; GRHL2; POU3F3; ZNF667; ZNF814; POU6F2; HOXA3; IKZF3; SOX1; NR6A1; GSC2; ACTL6B; ALX4; ZBTB20; KLF3; ZNF225; MED14; RFX1; ZNF112; ZNF81; KLF8; MYF5; RBPJL; HMBOX1; DLX4; FOXF2; KDM4C; TCEA2; POU2F3; HESX1; NEUROD4; IKZF4; ZNF334; THAP10; GLI2; NLK; TRIM22; HES2; SP4; HOXD12; ELF5; ZNF606; WHSC1L1; ZXDC; SOX14; ZNF688; SETDB1; HOXD1; ATOH1; ZNF816; NR4A1; NR5A2; IRF1; PPARA; ZNF165; HNF1B; PKNOX2; ELF4; PAX4; NEUROG2; ZNF354A; LZTR1; ZNF155; ZNF132; GCM2; ERBB2; ZNF611; ZNF234; VAX2; SCAI; PFDN5; POU1F1; HOXA2; PIAS1; TAF6L; ZKSCAN1; OVOL1; DOT1L; ZNF80; HSF4; HEYL; ZBTB7B; NANOG; LIN28A; VPS72; ZNF133; POU3F2; PRDM1; L3MBTL1; DMRT1; INSR; ZNF467; ZFP2; IKZF2; GATA1; ZNF674; NR2C1; PBX1; CDIP1; MEF2C; MED25; ZNF407; SIM1; JUND; PRDM16; ZBTB17; ZNF268; CUX2; ZFHX2; VHL; ZNF780B; LMX1B; ARID3B; ZNF394; ZKSCAN8; ZNF286A; ZNF124; HIC1; PHIP; LHX2; SRCAP; NR1H4; TBX10; TFCP2; ZEB1; MSX2; THAP9; HIC2; ZNF140; LBX1; KDM5C; ZNF613; ZNF480; BRDT; ZNF423; SHOX; CIITA; RSF1; NPAS1; TUB; LMO1; ZNF83; ZNF749; ZNF589; SNAI1; HNF4A; ZNF440; ZNF157; MXD3; ZNF442; NFE2; ZNF273; FOXI1; ATF7IP; MDM2; VGLL1; NR0B1; PIAS4; ASH1L; FOXG1; CBFA2T3; ZNF444; SALL1; ZNF432; ZSCAN2; DLX5; SUPT7L; ZNF770; TAF7L; UTF1; ZNF426; JAK2; ZNF135; ZNF215; ZNF136; ZNF430; FOXN3; PRDM13; ZNF264; NR4A2; ATF3; FOXA1; MDM4; ESRRB; ZNF34; RING1; HIRA; CERS4; HOXA6; MECP2; TBX3; SOHLH2; TAL1; ATF6B; NKX2-2; FLI1; ZNF12; NR1H2; ASCL2; CXXC1; ZNF208; BHLHE41; POU6F1; TOX; ZNF492; NAB2; HNF4G; SPDEF; SIX3; ETS1; CREM; TFDP3; WNT4; HOXA5; ZFP69B; BTG1; TCF7; MAK; HOXD3; TRPS1; ZNF623; HIPK2; BNC1; TBX6; MYBL1; PEX14; ONECUT2; SP2; ZBTB7C; USP21; SOX10; ARNT2; SMARCA1; FOXJ1; CITED1; TSG101; EP300; RXRA; PRDM5; TCF7L1; INSM1; SMARCC2; NEUROD1; SP140L; BAZ2B; MEOX2; TCF7L2; TCF4; MYRF; ZNF160; ZHX2; ZBTB43; CAMTA1; NKX3-2; ZBED1; ARID3A; SSBP2; E2F8; SOX5; STAT4; DMTF1; ZNF493; CITED2; ZIC1; TERF1; SHOX2; OLIG2; ZFX; EPAS1; NR2E1; ZKSCAN7; FOXE1; PEG3; ESRRG; TULP3; MYCL; TSC22D3; SUV39H1; ZFPM2; TRIB3; TLE4; KDM5B; FHL5; BRD4; MNDA; REL; MYT1L; MED13; HEY2; KLF11; BCL6; LYL1; ZNF652; TP63; EN1; NPAS2; ARL2BP; ZNF148; OSR2; ZMIZ1; CREB3L2; NFAT5; ZMYND8; CDX1; CHD9; BACH1; ZNF532; ZNF131; BNC2; NR2F1; MKL2; FOXF1; BBX; PBX3; TBX1; PGR; HAND1; ZNF544; POU2AF1; NR4A3; ZSCAN31; TOX3; ZNF232; FOXA2; EYA1; ZNF721; CD3D; SSX1; GATA6; TWIST1; KLF4; CTBP2; PITX2; PAX5; SPIB; TXNIP; TFEC; NCOA1; NKX2-1; NR3C2; SOX17; SOX9; AEBP1; FOS; CREB1; MEIS1; GATA3; ZNF586; E2F2
Down-regulation 132 MYC; PUF60; HMGA2; TFDP1; EGR1; NUP62; TCERG1; EZH2; RUVBL1; USP22; HSF2; MYCBP; RUVBL2; CBFB; TBP; FHL2; CCNA2; SSRP1; RBM14; FLNA; SF1; DDX54; PA2G4; TRIM28; DRAP1; PPRC1; SFPQ; UBP1; WHSC1; DR1; GTF2A2; PARP1; HNRNPD; NFIL3; EDF1; BRCA1; NFKB1; ETV1; ELK3; C1QBP; PTTG1; SMARCC1; CDK2; FOSL1; EED; BMI1; YBX1; CEBPG; ENO1; CHAF1B; RAN; SMARCE1; HMGA1; NFKBIA; MED6; UBE2I; ZNF146; DNAJC2; MYBL2; HOXC6; NPM1; SUB1; NELFB; PURA; TFAM; STAT5B; ETS2; FOXM1; YWHAB; POLR2A; NR2F2; BAZ1B; BAZ1A; ORC2; TBPL1; PSMC3IP; CARM1; PPP1R13L; ITGB3BP; RNF4; SNW1; PRKDC; ELF1; MLX; CENPF; CHD7; ADRB2; ZBTB18; MED1; FOXD1; RNF138; MBD2; CTNNB1; XBP1; GTF3A; MTDH; KLF2; E2F6; MLXIP; CEBPZ; PTRF; BCLAF1; SMARCD2; YBX3; PCGF2; HMGB1; HLTF; TRIM32; BIRC2; ERG; CCDC59; BLM; HMGB2; TSC22D2; HMGB3; TGFB1; THAP11; PITX1; SAP30; CTR9; HES1; RBBP4; NCOR2; IRX5; HSBP1; ID2; SMAD1; NRIP1; LEF1; ZFP36L1; PPARG; MAFB