Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16473 Radicicol GSE70138 MCF10A Human 24h 10uM EID0006
Types Number Response transcription factors
Up-regulation 243 BRF2; PHF1; ERBB4; HBP1; CALCOCO1; FOXO4; ATF3; RNF10; CIR1; NFE2L1; MAFG; PBXIP1; FOXJ3; KLF13; ATF4; NCOA2; TRIM33; ZNF394; ZNF117; NCOA3; ATF7IP; BTG1; BPTF; KDM2A; CEBPA; TFDP2; SMAD3; ZBTB43; DDIT3; EZH1; ZNF222; ZNF467; SPI1; BACH1; MXI1; ZNF136; ELF4; PIR; CLOCK; SAP130; IRF7; PIAS2; ZBTB40; HINFP; TMF1; ZSCAN31; LPIN2; TRAF6; CRK; HCFC2; KLF3; KDM5B; CEBPG; TXNIP; ZNF79; MED23; TFE3; ZNF44; TSC22D4; CBX4; SIN3B; ZNF506; ZNF12; ELF2; BCL3; PRDM4; BAZ2B; JAK2; TRIP11; ZNF331; HIC2; NFATC3; RBPJ; MED13; ZBTB11; ZBTB7A; HTATIP2; IRF1; ZNF443; ZNF83; FOSL2; ZNF350; MXD1; ZNF426; KLF11; FOXC1; UBE2B; KAT7; ZMYM2; ZNF14; ZNF84; ARID4B; BBX; NFAT5; RNF111; RCOR3; WWP1; NR4A2; ZSCAN16; BAZ2A; ZNF91; SUPT4H1; TCF15; KDM5A; HDAC5; KLF4; CUX1; NCOA6; KMT2A; ZNF264; NLK; ZNF10; FOXA1; ZNF217; ZNF175; ZNF711; HMBOX1; USP16; SREBF1; IRF2; NCOA1; SIRT7; ZNF415; NR1H2; ZNF212; ZNF189; TSG101; YAP1; PAWR; ZNF629; ZNF304; AFF1; ARID5A; DDX17; RYBP; NFYC; ZNF140; RXRA; DNAJC2; SP100; CREBZF; NPAT; NFE2L2; ZMIZ1; CBX7; TGIF1; MEF2A; PNRC1; ID4; NFE2; SIM1; TFEC; ZNF195; TCF4; PAX8; ZNF85; HIPK1; ATF2; ZNF468; MAF; CREB3L1; PBX2; TRIM16; BRD2; ZNF266; SIRT2; HOXB2; TBX3; RREB1; NKX3-1; ZNF345; SHOX2; ZNF148; HOXA10; TOX3; CITED2; POU2F1; ZKSCAN1; SERTAD2; CCNE1; KLF10; TCF7; ING3; NR0B1; MNDA; ZBTB1; MAFB; HEY1; JUND; VGLL4; SP2; ZMYND8; ZNF267; ELF5; RSF1; ARID3B; INSR; MEOX1; VEZF1; TOB1; TFAP2C; SMAD2; SP140; KAT6B; ZNF43; KAT2B; TWIST1; ZNF423; TRIM29; ATF5; ZNF165; MITF; SATB1; EP300; TAL1; OSR2; MAGED1; ZNF652; SIX2; HOXD1; LITAF; CERS4; PHF20; SIX1; TLE4; PHIP; MYCN; NR3C2; BRD4; NRBF2; DMTF1; DACH1; ZEB1; DLX5; LEF1; WT1; SSX1; BHLHE41; ZBTB18; KDM5D; TRPS1; CREB1; GATA3
Down-regulation 127 MYC; RUVBL1; TFDP1; HMGA2; CDK2; MYBL2; SSRP1; DNMT1; CCNA2; RUVBL2; SMARCC1; EGR1; NFKBIA; NOC2L; PRKDC; C1QBP; MYCBP; NPM1; FOXM1; EZH2; PPRC1; PARP1; TCERG1; ETV1; TRIM28; RAN; RBL1; PA2G4; ZNF146; ILF2; MYBBP1A; NFKBIB; ZBTB16; ACTL6A; CNBP; PTTG1; GMNN; NKX2-2; CBFB; FOSL1; HES1; SMARCA4; MTA1; ZNF22; TCFL5; WDR77; GTF2I; HMGB1; CAPN15; HMGA1; PMS1; RFXANK; HMGB3; CBX3; DEK; TTF2; ITGB3BP; APEX1; HNRNPD; RBBP4; MMS19; EDF1; TAF4B; HDAC1; ADRB2; WDHD1; YEATS4; PDLIM1; TAF9B; CALR; SNAI2; RNF4; ELK3; ZMYND11; HMGB2; TEAD4; MYBL1; CBX5; RBPMS; AEBP1; WHSC1; ZFPM2; SF1; CTNNB1; NUP62; PSIP1; LOXL2; NANOG; NR2F1; TOX; FHL5; ZNF593; ENO1; TCEA2; STAT3; CEBPZ; ARNTL2; RBBP7; WWC1; BLM; BMI1; BATF3; TCF21; TGFB1; NFIB; ST18; ETS2; ID3; INSM1; MYT1L; E2F5; CENPF; TGFB1I1; IFI16; EGR3; ETV5; GTF3A; PAX5; SUV39H1; SOX11; FOS; ID1; BHLHE40; EGR2; HLF; PLAGL1; ZFP36L1