Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16469 Withaferin-a GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 96 BRWD1; CALCOCO1; ZBTB3; PBXIP1; NCOA3; ZNF654; KLF13; INSR; PBX1; CBX7; BCL6; NANOG; AFF2; PAWR; IRF9; ZNF141; RFX7; ZSCAN18; ZNF532; ELF4; KLF5; SALL2; MEIS2; PNRC1; PEX14; SKIL; TCEA2; PBX3; NR1H2; ZNF415; MDM2; FEZF2; BARX1; ZNF225; ZNF268; ZKSCAN7; HLX; SOX18; ZNF254; FOSL2; HOXD1; CUX2; FOXN3; ZNF331; ST18; POU2AF1; TLE2; ERBB4; NFATC4; SOX3; ZNF423; TRIM16; BACH2; ARNT2; RSF1; ID1; IRF6; CERS4; HDAC9; NR5A2; ZIC3; TWIST1; SOX2; MEOX2; JUND; SIX3; SCAND1; SOHLH2; WNT4; ZNF512B; WT1; SOX13; SOX17; TRIM22; HHEX; SIX2; ZHX2; ETV5; ISL1; ZBTB20; NKX2-1; TP63; GATA6; ZNF91; VPS72; TOX; TFAP2C; BHLHE41; HLF; TRIM29; MEIS1; MECOM; SOX9; ID4; ZFP36L1; MAFB
Down-regulation 57 ATF1; EGR1; HMGA2; ITGB3BP; STAT5B; TCFL5; DNAJC2; HOXB7; HOXC6; BTAF1; SMARCE1; BMI1; ZNF146; CEBPG; EED; RAN; RUVBL2; ETS1; SMAD1; NUP62; SOX4; RBBP4; CREB1; ATF5; RNF4; EGR3; NFIL3; ZNF22; HLTF; KLF6; XBP1; BRD8; PURA; BRCA1; HMGB2; MTDH; CTR9; CCNA2; BATF3; BLM; TRIB3; NR2F2; CENPF; LEF1; NPM1; CHD7; HOXC10; BAZ1A; JARID2; NRIP1; BHLHE40; MYB; POU4F1; MSX1; TOX3; KDM5D; SUV39H1