Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16468 Withaferin-a GSE70138 MCF10A Human 24h 3.33uM EID0006
Types Number Response transcription factors
Up-regulation 482 HBP1; CALCOCO1; ATF3; DDIT3; ZNF117; TRIP11; ERBB4; FOXJ3; BRWD1; ZNF222; IRF9; HINFP; ATF6; MAFG; CBX4; NCOA3; BANP; ZKSCAN3; ZNF8; BRF2; KLF13; FOXO3; PHF1; ZNF423; GMEB2; ZNF202; TOX4; ZNF212; ZKSCAN4; JAK2; SPI1; EGR1; NFATC3; VENTX; ZSCAN31; TBP; HCFC2; HDAC5; MXI1; CHD2; KDM2A; GON4L; GBX1; NCOA2; PBXIP1; ZNF274; CAMTA2; HIVEP1; JUND; GABPB1; ARID4A; ZNF778; ELF4; CIR1; ZNF10; NRL; TFDP2; NFYC; LHX3; RSF1; HMBOX1; TRIM33; GLI2; ZNF91; TRAF6; TCF4; TULP2; PRDM2; ZBTB17; ARID4B; THRB; HOXB1; RAX; ZNF682; ZNF711; SIN3B; MNDA; ZBTB48; SIX6; HMGXB3; SAP130; TERF2; ZNF536; ATF7IP; HOXB2; TBX4; ZNF195; PKNOX2; NR4A1; ZNF331; NFATC1; ZNF24; ZNF362; WT1; NEUROG3; ZNF223; ETV2; NFE2; SUPT5H; BNC2; ZNF500; CAMTA1; HIF3A; ZNF354A; ZSCAN16; ZNF232; ZNF467; ZNF304; ZNF175; ZNF235; SUPT6H; GCM1; EZH1; SIRT7; ZNF345; BPTF; SUPT7L; ZNF264; CSDC2; PEX14; ZNF93; ZNF44; ZNF571; GATA1; NFAT5; SNIP1; ZNF770; RLF; DYRK1B; MXD1; TSG101; PRDM10; APBB1; NR2C2; ZNF75D; ZNF394; ALX3; PRDM14; SALL2; KMT2A; RORC; ING4; KDM5A; ZNF835; TBX21; WHSC1L1; ZBTB44; SCRT1; NR5A1; ZNF141; ZNF136; MYNN; IRF7; RING1; ZNF43; ZIM2; FOXO4; CRX; ZNF408; GTF2IRD1; ASCL3; ETV6; CEBPG; ZSCAN32; ZNF221; BARX1; PAWR; NOCT; BAZ2B; PHIP; TMF1; TFE3; ZSCAN9; ZNF426; RYBP; ZNF473; BCL6; SOX30; PRDM12; SNAI1; SHOX; ZNF85; MAML3; CBFA2T2; ZNF140; SHOX2; MYOG; MKL1; SKI; ZNF506; KDM4A; UBE2B; FOXH1; SOX21; CRTC1; HOXD1; ZNF671; SKIL; ZFHX2; CREB5; NHLH1; XBP1; HIRA; PEG3; ZKSCAN7; TDP2; ZNF549; ZNF471; RCOR3; ZFHX3; CDIP1; SOX2; ZNF814; IRF1; ZNF701; ZNF143; ZNF254; NPAS1; ZNF217; TBR1; MAK; CUX1; DPF2; ZNF415; SUPT4H1; FOSL2; IRF8; ZNF165; ZFP69B; MZF1; HOXC5; ZHX2; KLF1; ZNF268; PITX3; ZIC1; NKX3-2; SP2; ZNF675; MYRF; ZNF292; TULP1; HLX; ZBTB3; STAT2; HOXD3; ZNF214; CHD8; ZFY; ZBTB43; TEAD3; BRDT; ZNF287; SRY; ZNF34; TBX3; MYCL; RFX3; TCF7; SSX7; ZNF273; ZNF430; CREB3L1; PLAG1; L3MBTL1; ETV3; RBPJL; ZNF132; ZNF419; POU2AF1; ZKSCAN5; ZNF208; TEF; TSHZ2; ZNF334; ZNF507; FEZF2; SP4; ZNF154; AFF2; MYF5; DLX2; ZNF257; ZNF23; CRYM; PROP1; MED23; RXRB; FOXC2; ZBTB11; ZFPM2; ZNF764; MED13; FOXD3; ZNF253; ZNF14; RXRG; PIAS2; ZNF444; TSC22D3; PNRC1; ELK4; PRDM9; BACH2; KLF3; LDB1; ZNF606; CARF; RBBP5; HOXB8; BACH1; NFATC4; HOXB13; USP16; TSC22D2; ZKSCAN8; LZTR1; ESRRB; ELF2; MAFB; ZNF329; CCNE1; ZNF225; ZNF81; PBX2; ATF4; POU2F3; ARHGAP35; NEUROD4; ALX4; LMX1B; DCC; NPAT; TRIP4; TLX3; ARNT; TGIF1; CREB3L2; NLK; ZNF695; MDM4; HESX1; ZNF12; SRCAP; SOX18; IKZF3; ZNF350; GFI1B; ANKRD1; ZNF133; RNF111; MEF2A; BCL11A; MEIS2; HOXD11; ATOH1; ZNF248; SOX5; ZNF112; PRRX1; SOX1; FOS; MAFF; NFE2L1; ZNF442; WNT4; GCM2; NFRKB; SREBF1; ZNF573; THAP7; NANOG; ZSCAN18; MEF2C; CHD3; ZNF674; TFEC; DLX5; ZKSCAN1; FOXD1; EP300; THRA; ZMYM2; CUX2; TRPS1; HIPK1; ZNF529; SIRT2; SOX11; EYA1; ZFHX4; ATN1; SIX2; ZNF652; ZNF157; ZNF80; ZNF266; PAX6; BRD4; MECP2; TAL1; ZNF557; ID2; YAP1; TULP3; TCEA2; KDM5B; ZNF665; AR; KAT2B; ISL1; HIC2; CIITA; TRIM29; BTG1; SOX3; ZNF611; GRHL2; FOXF1; NKX3-1; SSX1; ARID3B; DAXX; MAGED1; ZNF432; TRIB3; CBFA2T3; NR4A3; TOX3; RBPJ; CEBPA; INSR; JUNB; SIX1; CERS6; FOXF2; BHLHE41; KLF10; ZNF589; SIX3; ARNT2; KDM5D; MYCN; MEIS1; EBF2; CERS4; KLF4; MEOX2; AGO2; DACH1; PITX2; STAT4; ZNF468; TLE4; KAT6B; VPS72; SOX9; PBX3; ZNF131; SPDEF; ARID5B; GATA6; FOXG1; ID4; TWIST1; REL; CHD9; ZBTB20; TFAP2C; EGR3; CREB1; LEF1; HDAC9; ZBED2; FOSB; CD3D; SOX17; SPIB; TRIM24; NCOA1; IRF4; FOXA2
Down-regulation 120 MYC; TFDP1; RUVBL1; HMGA2; CCNA2; RHOA; SSRP1; RUVBL2; CDK2; PA2G4; C1QBP; TCERG1; FOXM1; PUF60; MYCBP; NELFB; TRIM28; SUB1; CBX3; ATF1; PTTG1; HMGB1; HDAC2; EDF1; PCBD1; ITGB3BP; HES1; BMI1; UBE2I; CBFB; RNF4; CENPF; SMARCC1; NRIP1; BRCA1; DDX54; PRKDC; HMG20B; GTF3A; EZH2; PARP1; ZBED4; NPM1; MYBL2; DNMT1; WHSC1; HOXA10; STAT5B; NFIB; RBPMS; TCFL5; GMNN; RBBP7; NFKBIA; UBP1; SOX4; NOC2L; GTF2I; PMS1; NAB1; RBBP4; CENPB; CTNNB1; ZNF146; ZNF32; RAN; BCLAF1; NR2F2; TRIM32; HNRNPD; MED24; HMGB2; YWHAB; RBM14; STAT6; HOXC6; ZBTB38; HMGA1; CIZ1; PSIP1; SMARCE1; MYBL1; NONO; ILF2; SLC2A4RG; XRCC6; HDAC1; TGFB1; ELK3; RBBP8; ZNF22; YBX1; THAP11; BRD3; NR2F1; PURA; DEK; CEBPZ; CHD7; ID1; HMGB3; ADRB2; PTRF; ENO1; ZFP36L2; ELF1; TGFB1I1; RNF14; MKL2; BIRC2; BATF3; WWTR1; APEX1; HOXB7; HOXC10; HOXA5; SUV39H1; HMGN3; AHR; IKBKAP