Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16467	Withaferin-a	GSE70138	MCF10A	Human	24h	10uM	EID0006

Response Information :

Types	Number	Response transcription factors
Up-regulation	98	EGR1; HOXB13; FHL2; IRF9; ATF3; NR4A1; HOXB1; MED15; CALCOCO1; NAB2; SMAD3; HOXD13; CBX4; XBP1; PBXIP1; FOS; KLF4; IRF7; ZMIZ1; PPARD; CITED2; FOXF2; ZFPM2; ZNF350; WWP1; HMGA2; ZSCAN16; PPP1R13L; NFKB2; PAWR; THAP7; SOX18; AR; MEOX1; NR1H2; CRYM; JUNB; HOXD3; GATA6; ZNF415; CERS4; GRHL2; DLX4; NKX3-1; FOSB; LMCD1; BARX1; TGFB1; NR0B1; BTG1; TULP3; CREB3L1; EGR3; CDX1; ZSCAN31; RORA; SOX4; SOX3; JUND; LOXL2; ZNF165; ZBED2; HIC2; WT1; ARNT2; NFE2; TFAP2C; ID2; TGIF1; HOXD1; RUNX3; LIN28A; MNDA; NR4A2; PITX2; VDR; TGFB1I1; EGR2; DAXX; OSR2; JUN; CTBP2; NFE2L3; EYA1; TRIM22; TP63; BASP1; FOXF1; MEIS1; GATA2; ZNF91; DLX5; IFI16; SOX17; SPIB; SSX1; ZFP36L1; TWIST1
Down-regulation	86	MYC; HDAC2; PRKDC; NFKBIA; CRK; NR3C1; CNOT1; FOXJ3; FOXO3; KAT6A; PAXBP1; ZNF24; BMI1; HSF2; ASH2L; RB1; ZMYM2; PBRM1; ZNF146; HLTF; ARID4B; SUZ12; NFIL3; UBP1; MTDH; SSRP1; ZMYND11; CHD7; HIPK3; MTA1; ATF2; CENPF; WHSC1; NAB1; CHD1; KMT2A; ATF1; MLLT10; ZNF217; RFX7; ADNP; MED1; FUBP1; MKL2; NCOA6; SREBF1; CCNA2; PURA; BCLAF1; TCF12; NRIP1; SPEN; CCNC; CHD9; HES1; GTF2I; DEK; MGA; ENO1; RBBP4; CRY1; SP3; BAZ2B; HDAC4; PMS1; CTR9; SMAD4; BAZ1A; CBFB; RBM14; HOXA5; ZEB1; HMGB3; NR1D2; KLF9; CTNNB1; CEBPZ; KDM5B; NFIB; PBX3; TRRAP; ASCL1; ZBTB18; SMAD1; AHR; ATF5