Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16466 Mitoxantrone GSE70138 MCF10A Human 24h 0.04uM EID0006
Types Number Response transcription factors
Up-regulation 38 ZNF654; CALCOCO1; HOXB5; TRIM22; HOXB6; CRYM; ZNF268; MDM2; MYT1L; HDAC9; IFI16; TCEA2; ARNT2; SOX17; FOSL2; CERS4; TLE4; IRF6; BACH1; ZBED2; ZIC1; VDR; ARID5B; SHOX2; ZNF281; WT1; DLX5; MYRF; HOXB2; EMX2; HLF; TRIB3; ID1; ID3; MEIS1; FOS; MEIS2; MECOM
Down-regulation 42 EGR1; ATF1; SFPQ; EZH2; SMARCE1; DDX5; HMGB2; NRIP1; HNRNPD; CTBP2; RBM14; NPM1; CREB1; WWTR1; KLF2; HLTF; HOXC6; BCLAF1; SOX4; CRY1; DEK; VEZF1; ZBTB38; FOXC1; NR1D2; ENO1; PITX1; KLF9; NR2F2; TXNIP; ZBTB20; BCL11B; DACH1; MYB; HSBP1; ZNF721; AEBP1; HOXC10; HMGN3; PEG3; IRF4; SUV39H1