Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16465 Mitoxantrone GSE70138 MCF10A Human 24h 0.37uM EID0006
Types Number Response transcription factors
Up-regulation 52 TRIM22; RFX5; PBXIP1; CALCOCO1; ZNF195; IRF9; CREBL2; SP100; CIR1; HOXB13; ZNF768; BCL3; HBP1; ZNF83; TSG101; SOX15; TAF10; ELF3; FOSL2; CBX7; ZNF44; ZNF264; IRF7; AR; PNRC1; ZBED2; STAT1; SP110; ZNF692; IRF6; SMARCA1; TRIM16; ERBB2; BNC2; SALL2; CERS4; ZNF544; ZNF226; ZNF611; ZSCAN18; TCF4; ZNF160; ZNF91; ID2; BHLHE41; TRIM29; MAF; ZNF652; SOX9; ESR1; FOS; BASP1
Down-regulation 64 EZH2; MYBL2; CCNA2; FOXM1; TFDP1; HMGB2; PTTG1; CENPF; TAF5; SAP30; DEK; WHSC1; ITGB3BP; YEATS4; NUP62; CHAF1B; ATF1; BRIP1; GMNN; PARP1; NRF1; TLE1; TAF4; FOSL1; AGO2; RNF138; KMT5A; RBL1; TAF9B; PA2G4; WDHD1; HMGB1; PURA; BLM; BATF3; RBM14; DR1; HNRNPD; SFPQ; HHEX; HMGB3; E2F8; RAD21; BAZ1B; NFYB; HMGA1; RBBP4; NR2F2; NFIB; BCLAF1; NPM1; SMAD1; BRCA1; CHD7; CBFB; SATB2; ZEB1; PAX5; EGR3; PSIP1; PITX1; MAFB; SUV39H1; KDM5D