Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16464 Mitoxantrone GSE70138 MCF10A Human 24h 3.33uM EID0006
Types Number Response transcription factors
Up-regulation 399 CALCOCO1; ZNF415; IRF9; ERBB4; HBP1; CDIP1; KLF13; PRDM2; SUPT7L; ZNF667; NFATC3; TRIM22; ATF3; NR5A1; ZNF223; HOXB1; ZNF79; DYRK1B; CBX4; ING4; MNT; ZNF331; ZNF91; CREBL2; ZNF117; VENTX; ZNF665; CRX; BHLHE41; SRCAP; CBFA2T2; PBXIP1; HOXB5; ZNF345; L3MBTL1; BRWD1; ZNF268; SALL2; PNRC1; CHD2; ZNF500; ZNF688; IRF6; ZNF571; SPI1; ZNF536; ST18; ZNF682; ZNF224; NEUROG1; ZNF471; ZNF85; TULP2; ZNF75D; ZNF257; ZNF264; ZNF711; TFAP2A; BNC1; MAML3; ZNF154; ZNF195; ZNF606; CUX2; FOXF2; HIF3A; ZNF219; PRDM1; SIX6; NEUROG3; SOX2; ZNF362; EMX1; HOXB13; ZNF350; ZBTB44; ZNF354A; KLF11; ZNF221; ZNF671; CBX7; CAMTA2; ZNF573; TBX4; GBX1; TBX21; ZNF222; LHX3; HINFP; ZNF669; FEZF2; TSHZ2; DCC; ETV2; ZKSCAN4; MKL1; BRDT; PRDM14; THRB; FOSL2; ZSCAN18; IRF1; ZNF701; CSDC2; ZBTB3; PRDM12; SRY; PROP1; ZNF235; HOXD1; ZNF133; ZNF611; SOX3; SIN3B; NHLH2; ZNF43; ZNF141; ZNF74; GON4L; ZNF112; RARG; ZNF334; MYCN; CARF; POU3F4; ZFP2; ZNF214; POU4F3; ZNF239; ZSCAN9; TBX5; LZTR1; TRIM29; SCRT1; ETV7; JUP; ZNF208; TCEA2; ZNF205; ZFPM2; NFATC4; ZNF10; ZNF81; ZNF550; SCAI; IRF7; FOXN3; HDAC5; ZNF177; NEUROD2; TP73; ZNF549; ZXDB; PRDM9; TBR1; ZNF749; FOXE3; RFX3; POU2F3; PHF1; EVX1; HOXB3; NEUROD6; ZNF140; ZNF506; ZNF232; TAF6L; ASCL3; PAWR; FOXH1; VPS72; ZKSCAN7; PEX14; STAT2; POU6F2; ZNF135; AFF2; ZNF623; ZNF426; CBX2; ZNF175; E4F1; CEBPE; MYF5; ZNF440; ZNF44; NCOA2; HOXD12; SSX7; GCM1; BARX1; ZNF93; CERS4; PRRX1; ARID5A; KLF3; CREB3; RING1; DLX4; TBX3; ESRRB; ZNF423; ZNF80; ZFY; ZNF132; CDX4; ZNF225; NANOG; ZBED1; TAF7L; SOX4; ZNF155; OVOL2; ZNF780B; MDM2; HSF4; UTF1; ZMIZ1; VHL; HOXB2; HDAC9; GBX2; HIC2; ZNF419; EPAS1; ZBED2; HOXA3; TP63; TBX6; TBX10; ZIM2; SKIL; NFKB2; SOX18; GLI2; ZNF287; ZNF215; ZNF768; ZNF136; ZNF165; ZFP69B; TULP1; ZNF674; HES2; ZNF529; ZNF695; ZNF512B; BPTF; GFI1B; HMBOX1; ACTL6B; GSC2; NEUROG2; SOX1; ZNF329; EZH1; GCM2; PCGF3; ZNF83; RORA; POU4F2; ELF4; NHLH1; NR4A3; MYT1; SP4; LIN28A; MED12; MBD4; SUPT6H; MYRF; CREM; STAT4; SETDB1; NFE2; ZIC3; BACH2; ZNF304; TULP3; ZNF157; ZNF180; ZNF589; ZNF407; WNT4; POU1F1; PAX4; FOXO4; ZNF217; AHR; ARID5B; CIITA; IKZF3; ZNF254; GATA6; GRHL2; POU2F2; AES; SKI; MXI1; NR4A2; TFDP2; TBX1; SNAI2; PBX1; MEIS2; TLE2; TCF4; ZNF492; PBX3; MAF; SOX17; MEIS1; ZNF544; TRIB3; ZNF14; SP110; FOXE1; KAT2B; WWC1; PKNOX2; DLX5; ZFP36L2; ARNT2; TAL1; PEG3; ZNF432; TAF7; SMAD3; HLF; NFE2L3; TGIF2; ZBTB43; NR5A2; ARID3B; RSF1; KLF4; CBFA2T3; ZNF160; EP300; VGLL1; NKX2-2; HOXB6; SOX9; SOHLH2; MECP2; ZKSCAN1; TERF1; KLF7; PAX6; ARL2BP; NR4A1; ZSCAN31; BCL6; TFAP2C; ZNF652; HLX; ID1; ZNF12; INSR; BNC2; BTG1; TOX3; REL; NR1H2; HEY1; INSM1; NR1D2; NEUROD1; ID4; ARID3A; DACH1; MXD4; OSR2; MECOM; FLI1; BCL11A; MEOX1; MED13; TOX; TWIST1; TSC22D3; ID3; ZHX2; TFEC; TXNIP; NKX2-1; EGR2; SPDEF; FOS; FOXF1; ETV5; IFI16; SMARCA1; TRPS1; SPIB; WT1; KDM5D; RELB; CREB1
Down-regulation 120 EZH2; CCNA2; PCBD1; PUF60; ATF1; MYC; TFDP1; RHOA; SSRP1; RUVBL2; NUP62; HSF2; HMGB2; HMGA2; BCLAF1; BAZ1B; CBFB; CENPF; RBM14; PARP1; ITGB3BP; RUVBL1; TRIM28; PTTG1; FOSL1; SUB1; ZNF146; GTF2A2; SFPQ; PA2G4; DEK; NPM1; SMARCC1; TCERG1; HDAC2; BRCA1; FOXM1; TBP; UBP1; SMARCE1; NFYA; EED; HOXC6; NR2F2; RBBP4; NCOA4; CHAF1B; HNRNPD; GMNN; RNF138; HMGB1; RNF6; MBD2; RAN; CCDC59; TAF5; ECD; ORC2; XBP1; PURA; JARID2; CBX5; CCNC; BMI1; MAX; MED6; BAZ1A; SNW1; DNAJC2; NELFB; PRKDC; HLTF; HOXC10; EDF1; ENO1; MED1; RBBP7; NONO; BLM; SAP30; MLX; CALR; SAP18; XRCC6; SMARCD2; HMGA1; MTDH; CHD7; CTR9; ZBTB18; CTNNB1; SAFB2; AATF; SATB2; NFIB; PITX1; ELF1; HDAC1; FOXD1; C1QBP; TBL1XR1; GATAD2A; TRIP6; CITED2; RBBP8; IRX5; CDK8; EYA2; REPIN1; CEBPZ; CEBPA; YWHAB; TRRAP; KLF2; PIR; ETS2; HMGB3; WWTR1; SUV39H1; ELK3