Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16463 Mitoxantrone GSE70138 MCF10A Human 24h 10uM EID0006
Types Number Response transcription factors
Up-regulation 170 IRF9; CALCOCO1; PRDM2; TRIM22; CBX7; SP110; SP100; PBXIP1; NR5A1; IRF7; CBX4; HBP1; LZTR1; ZNF117; TCEA2; SIN3B; CAMTA2; JUP; CDIP1; KLF13; STAT2; ZNF536; L3MBTL1; NFATC3; ZNF444; BNC1; GLI2; ZNF415; MZF1; CREBL2; ZNF268; PHF1; ZBED2; HOXB13; ZNF337; IRF6; AFF2; ZNF665; RING1; MNT; HIF3A; ZNF768; MDM2; HDAC5; ZNF83; ATF3; TCF4; MED15; SMARCC2; ING4; PRDM12; FOSL2; SALL2; ZNF500; ZBTB44; ZNF331; CERS4; ZNF75D; ZNF345; ZFPM2; KLF6; AES; SETDB1; SOX15; BARX1; BPTF; RBPJ; SRCAP; ZNF224; NHLH2; SOX4; TLE2; ZMYND8; ERBB4; BCL6; KAT2A; PNRC1; ST18; ZNF350; TAF1D; CARF; WNT4; HMBOX1; SNAI2; PAWR; ZNF611; ZNF573; SP140; FEZF2; MYRF; SPDEF; ZNF91; IRF1; TP63; NEUROD1; PEX14; ZNF467; VPS72; NCOA2; MEOX2; ZNF512B; BACH2; ZNF623; ZNF606; SKI; SOX3; CREB5; SOX18; PCGF3; KLF4; HOXD1; NFATC4; TBX1; CBFA2T3; FOXF2; HIC2; TGIF1; ZNF692; NANOG; BTG1; SP140L; KLF11; SOX2; ZBTB20; ZNF43; TLE4; GATA6; TFAP2C; MXI1; JUN; STAT6; BNC2; KAT2B; MYCL; ERBB2; STAT1; ARNT2; NPAS2; TRIM29; ZNF160; INSR; NR4A2; RORA; NFE2L3; TCF21; ZIC3; TBX3; BCL11A; PFDN5; ARID5B; TRIB3; TXNIP; DLX5; NFE2; ZNF589; ZHX2; TULP3; MEIS1; MEIS2; HDAC9; SOX17; EMX2; BHLHE41; PEG3; SOX9; TFEC; SMARCA1; ZNF652; FOS; KDM5D
Down-regulation 75 EZH2; TCERG1; TFDP1; CENPF; HSF2; RUVBL2; HMGB2; PTTG1; FOXM1; HDAC2; SSRP1; NUP62; GMNN; MYC; PARP1; RHOA; BCLAF1; SUB1; CBFB; CHAF1B; RBM14; CCNA2; SAP30; EED; MYBL2; BAZ1B; WHSC1; TAF9B; CHD1; HNRNPD; PRKDC; ING3; ATF1; SFPQ; DEK; MTDH; CCNC; HLTF; AGO2; VGLL4; BRD3; MEF2A; TFAM; HOXC6; STAT3; BLM; RBBP4; C1QBP; TRIM28; CBX5; MED1; NR1D2; RBBP8; MAFB; RNF14; HSBP1; CALR; XBP1; ENO1; NPM1; SMAD1; ECD; RBPMS; WWTR1; HOXB7; BAZ1A; SOX11; PITX1; IRX5; NR2F2; HMGB3; MNAT1; LEF1; SUV39H1; BASP1