Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16459 Brivanib GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 48 SSBP2; GATA2; BRWD1; EGR2; NRBF2; THAP10; HOXA10; ZNF227; MYBL1; HIPK3; NFIB; ZNF239; RCOR3; CNOT6; JARID2; PBX1; BLM; FOXC1; ZEB2; AR; HMG20A; NR2F1; PPARGC1A; BCL6; IRF7; IRF9; OLIG2; EHF; FLNA; MNDA; ANKRD1; SOX11; WT1; HOXC10; MAF; TFEC; TOX; BHLHE41; TWIST1; TXNIP; SATB1; BASP1; GATA6; MEIS1; SMARCA1; NKX3-1; HOXC6; ZFP36L1
Down-regulation 31 IRF1; CNBP; DNAJC1; TDP2; AES; JUNB; BCL3; DLX2; BCL11A; FOXD1; TGIF1; NR1D2; LITAF; ZMYND8; DLX5; ZNF91; BMI1; ID3; ZFP36L2; KLF5; ZSCAN18; MKL2; TCF4; CREG1; FOSB; REPIN1; ID1; CREB3L2; ZHX2; TRIM29; FOS