Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16447 As-601245 GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 634 NFKB2; CSDC2; FOXO4; GLI2; ETV1; NFATC4; PRDM2; CEBPA; FOXN1; PBXIP1; PAX1; EGR3; GLI3; GRHL2; OVOL1; SOX2; TEAD3; AR; RARG; NRL; PDX1; ZNF76; GCM1; PAX9; SIX6; TEF; GBX1; RHOA; ZNF506; CBX4; ZBTB48; HOXC13; HAND2; NEUROG1; INSR; RERE; CBX7; CHD2; PPARD; SCRT1; NR0B1; ZNF189; ESR2; ZNF415; RXRG; AFF2; TFAP2C; ZNF764; BRF2; CBL; STAT2; CITED1; EMX1; FOXB1; ZNF467; HOXC4; STAT5A; HOXC6; TCF7L1; KLF1; FOXA1; GLI1; TFEC; ARRB1; SOX10; SSX7; TULP2; BRPF1; WHSC1L1; ZBTB44; LMCD1; GON4L; ZNF688; CREB5; HOXD13; CRYM; NEUROG3; ZFY; WNT4; VGLL1; VENTX; ZNF671; NR6A1; NR5A1; ZIC4; WIZ; ZIM2; TAF5; KAT8; OVOL2; ZNF768; BRWD1; ZNF174; CALCOCO1; NEUROD4; PAX7; ZNF274; PRDM8; PBX2; NAB2; BRDT; ZNF778; HDAC11; NFIL3; SRF; ALX1; NKX2-5; HINFP; EYA2; TADA2A; HOXB1; THRB; TBX19; TBX4; HOXC11; FOXD3; SUPT4H1; SOX21; CRX; HDAC5; SOX5; MYOG; NHLH1; ETV2; PIAS4; ZNF343; GATA1; TLX3; HIC2; SRCAP; ZBTB25; ZNF549; ZBTB7B; PRDM13; ASH1L; SHOX; ZNF460; HNF1B; ASCL3; PITX3; RFX3; ZNF672; GATA4; GMEB1; POU2F1; NFATC1; ZNF701; ZNF264; HMG20B; GFI1; HHEX; DCC; ONECUT1; HOXC10; MYCN; STAT5B; SIAH2; SOX13; FOXE1; BCL11A; E2F8; ZNF362; TCF7L2; BCL6; FOXE3; FLI1; ZNF324B; ZNF34; FOXH1; CBX8; ZNF132; VHL; CBX2; NFYC; PAX3; PRRX1; FOXL1; ZNF471; TRIM33; ZNF7; FEV; WT1; TBR1; HIC1; ZNF83; ZNF835; ZNF208; ERBB4; ZIC3; MAF; ID4; FOXC2; PRDM9; ZNF234; ZNF556; PSPC1; IKZF4; TRAK1; CRTC1; GSC2; ZNF507; ZEB2; OSR2; NR0B2; SALL2; RSF1; NEUROD2; DBP; HOXD11; EN2; ZNF41; SOX14; ZKSCAN4; ZSCAN32; HOXC8; ZNF154; BNC2; GFI1B; RAX; HOXD9; RORB; ZNF500; TP73; NANOG; TLE4; SETDB1; PRDM16; ZBTB39; KLF13; KDM5D; SSX1; SP1; ZNF446; ZNF286A; ZNF257; KLF8; TLX1; RBPJL; THRAP3; ZNF695; TBX21; HOXA11; NR1I3; ATOH1; IKZF2; BATF; SNIP1; PAX2; ZNF117; TRAF6; POU6F2; BTG1; SOX30; DYRK1B; ZNF221; HOXB8; YBX2; TAF1C; ARID5A; FOXD2; GCM2; ZKSCAN3; MLLT1; BACH2; KLF15; ZNF81; ZNF814; ZMYM2; ETV3; ZNF124; POU4F3; CDX4; HOXC5; TSC22D4; RARA; HIF3A; DOT1L; HNF4A; ALX4; ZNF267; MAML3; AEBP1; SOX3; E2F2; ETV6; ZNF175; ZNF816; TAF6L; MNDA; SUV39H2; PRDM14; SRY; TLX2; MXD3; ZNF236; ZNF550; HOXA10; IFNB1; ARHGAP35; KDM5B; ZBTB3; ZNF682; ZNF613; GRIP1; NEUROD1; ZXDC; ARNT; NR5A2; GATA6; PAX4; PPARG; HOXD10; CBX6; TFAP2B; ZNF391; ZNF93; ZNF674; CAMTA2; HOXD3; PRDM1; ZFP2; SHOX2; TAF4; ZFP37; HOXA2; ZNF157; LHX3; NKX3-2; RXRB; MYF5; ZNF282; MBD4; HESX1; SP140; SSX3; MED31; IRF2; IRF6; SOX1; JAK2; SCMH1; ELF2; ASCL2; CIITA; ZNF512B; MSX2; ZNF248; TRPS1; HMX1; ZNF287; ZNF324; KLF4; APBB1; ZNF80; ID2; VAX2; BARX1; CERS4; ZNF407; NR1H4; L3MBTL1; HEYL; HSF4; HLTF; ZNF214; ALX3; LBX1; ZNF141; TAF4B; ZNF780B; TCEA2; IRF5; KLF11; FOXO1; LIN28A; HAND1; POU6F1; TULP1; ZNF667; ZNF8; AIRE; IL16; ZNF516; TCF21; KLF3; ZNF492; ZNF783; TOX4; PCGF1; PRDM5; MEOX1; SERTAD2; ONECUT2; ZNF14; POU3F4; TADA3; IRF8; KMT2A; ZSCAN31; ZNF440; ATF7; PGR; ZNF749; IRF9; ZBTB7C; USP21; ZNF211; TBL1Y; AFF3; IRF7; HEY2; HDAC4; PAXBP1; BRCA2; CARM1; ELF5; MNX1; NFIX; MED24; PAX5; LHX1; PHF8; NR2F2; RUNX2; ZNF629; SOX18; ARID1A; CITED2; TOX3; ZNF136; STAT4; FEZF2; KAT2B; TXNIP; IRX5; CHD8; SAP130; BAZ1A; ARID4B; RFX2; FOXL2; RFX1; ZNF813; ZKSCAN7; EYA3; ASCL1; TAF1A; POU1F1; BAZ2A; MED20; ACTL6B; SIX1; PPARA; ZNF574; TSHZ2; SIRT7; POU2F3; MEF2C; ARID3A; MEN1; HOXD12; RARB; ZNF135; ZNF536; PEG3; IKZF1; POU3F3; TAF1; ZNF710; INSM1; ZNF75D; ZNF665; CEBPE; SNAI1; PCGF2; RXRA; BCL10; NEUROG2; PRDM12; MAFG; OLIG2; NKX2-8; ZNF442; ING1; SMARCD3; NHLH2; POLR2A; ESRRG; ZNF444; EZH2; PROP1; HNF1A; MYT1; KLF10; LZTR1; ESRRB; ZNF493; NR1H3; NKX3-1; ATF6B; ZNF473; NFE2; THAP9; FHL5; TBX5; ZNF253; MSC; SSBP3; HR; TCF15; MYCL; IKZF3; MLXIPL; ZNF528; ZNF224; ZNF329; ZNF148; ZNF426; ZNF675; PKNOX1; BARX2; MXD1; SMARCD1; RBPMS; CDYL; DLX4; ING2; ZNF334; CARF; NCOA1; TBX3; PRMT2; HES2; CREB3L1; ZBTB14; RUNX3; ZNF225; PRRX2; TLE2; TAF11; SP4; ZNF623; LDB1; ZNF611; SMARCA1; POU4F1; KMT2D; WWP1; EP300; PBX1; FOXI1; HNF4G; BACH1; MITF; SIX2; TGFB1I1; IRF4; HEY1; ZNF419; NACA2; UBTF; TFDP3; ZNF384; CDIP1; ZKSCAN8; CBFA2T3; EYA1; TBX1; SUPT6H; ING4; ZNF551; ZNF573; SLC2A4RG; LYL1; VPS72; HMG20A; NPAS2; ESR1; PAX6; SPDEF; HMBOX1; ZNF254; NFE2L3; NCOA2; ZKSCAN1; FOXN3; CHD4; MYRF; KAT7; KLF7; ZNF652; NR4A1; IRF1; PROX1; POU2AF1; ZSCAN18; CD3D; TCF7; DLX2; SP140L; RREB1; TP63; BCOR; CREB3L2; ANKRD1; DNMT3B; TGIF2; ZBTB16; ZNF160; EGR2; SIX3; FOSB; MEOX2; THAP11; SOX11; DLX5; HOXB2; ZEB1; NKX2-1; BRD4; GATA3; JUN; FOXC1; PLAGL1; HLF; HOXD1; KLF2; ZNF107; PITX1; FOXA2; MEIS2; IKBKAP; GATA2; SOX17
Down-regulation 151 USP22; CBFB; HMGA1; CCNH; RUVBL2; TFDP1; COPS5; ZNF195; TBP; HNRNPD; YBX3; CBX3; TOB1; TGFB1; DDX5; ERBB2; EDF1; ID3; ZMYND11; CNBP; SFPQ; ID1; GTF3A; TDP2; TCEA1; CDK2; USP16; MED21; PRKDC; DEK; RUVBL1; BTF3; SETD3; ZNF432; SP100; TRIP6; ZBTB38; ETS2; KLF5; YWHAB; CNOT6; TEAD4; CNOT1; ELF1; DNAJC2; RFXANK; IFI16; HOXA5; TCF25; CTCF; NR2C1; PFDN5; HMGB1; MTDH; ENY2; HDAC6; MNT; MBD2; ZNF302; CEBPB; TSC22D1; YAF2; RFX5; CSDE1; ZNF593; TSC22D2; RBL2; BIRC2; PA2G4; CRY1; UBE2B; TAF10; PHF20; SUPT5H; RNF111; MED6; PSIP1; SF1; YBX1; HIPK1; COPS2; SMAD3; CEBPG; ENO1; PPP1R13L; CBX5; TRIM29; NAB1; SOX4; WWC1; ELK3; THAP10; RNF141; CEBPD; CREB3; PDLIM1; BCL11B; VDR; STAT1; TMF1; GTF2IRD1; ZNF232; UBE2I; ZNF580; XBP1; VEZF1; NFIB; TFCP2L1; MYBL1; NCOR2; ABL1; PURA; HSBP1; ZNF423; ATF5; TERF1; ZNF165; ETS1; RNF6; FOXD1; PTTG1; GTF2I; ARL2BP; FOXG1; RBBP4; BHLHE40; SOX9; MSX1; ZFP36L1; HIRA; ZNF43; NPM1; MED14; PBX3; ZNF532; ATF3; NR2F6; CUX2; AFF1; ZFP36L2; TRIB3; ZNF226; HDAC9; CREB1; FOXF2; ADRB2; MXI1; LITAF; FOXF1; MECOM; FOS