Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16445 Linsitinib GSE70138 MCF10A Human 24h 0.04uM EID0006
Types Number Response transcription factors
Up-regulation 22 GATA2; KDM5B; IRF6; ZNF589; HOXA10; GRHL2; ZNF165; WT1; HOXD1; WWC1; NR0B1; KLF11; NFE2; TRIM16; ADRB2; ARNT2; TRIB3; MAF; TFAP2C; OSR2; HOXB2; MEIS1
Down-regulation 14 MAGED1; CBFB; JARID2; SATB2; NFIB; KLF2; ZEB1; IRX5; EGR3; TOX3; MYB; LEF1; HOXC6; FOS