Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16443 Linsitinib GSE70138 MCF10A Human 24h 0.37uM EID0006
Types Number Response transcription factors
Up-regulation 38 PBXIP1; ZMIZ1; EHF; CREBL2; BNC1; ZNF165; KLF4; PBX1; GRHL2; IRF6; NKX2-2; BTG1; MEOX1; ARNT2; NFE2; NFATC4; STAT6; ZNF423; LIN28A; NR4A3; CTBP2; ZBTB16; TLE4; TGFB1I1; HTATIP2; TXNIP; CITED2; FOXF2; TFAP2C; ZHX2; TSC22D3; TRIM22; PITX2; SOX17; TRIB3; BASP1; TRIM29; MEIS1
Down-regulation 14 DNAJC2; TBL1X; SERTAD2; RBBP7; BMI1; CTR9; SATB2; CHD7; MSX1; LEF1; DACH1; KDM5D; PPARG; GATA3