Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16442 Linsitinib GSE70138 MCF10A Human 24h 1.11uM EID0006
Types Number Response transcription factors
Up-regulation 59 STAT5B; CITED2; PBXIP1; GATA2; TXNIP; IKZF1; CREBL2; TSC22D3; CALCOCO1; ELF3; KLF4; PRDM1; ZNF688; IRF5; TADA3; HOXB6; MYBL1; SNAI2; TBX2; RCOR3; BACH1; TRIM16; FOSB; HOXB7; PNRC1; HIPK3; MNDA; FOXC1; SMARCD3; KLF2; ERBB2; RBPMS; NFE2; LMCD1; TFAP2C; NFE2L3; TRIM29; ZEB2; HIPK1; SSX1; BCL6; IFI16; MITF; FLI1; PBX1; NR2F2; BASP1; ZIC1; BTG1; MAF; DNMT3B; HOXB2; PLAGL1; SMARCA1; MECOM; ELK3; TWIST1; MEIS1; MAFB
Down-regulation 30 YEATS4; SFPQ; RBM39; ING1; ZNF331; MAFF; PAX5; PURA; FOXD1; INSM1; SIM2; CBX5; ERG; ZNF394; NKX2-2; JUNB; AGO2; IRF8; ZNF281; ZBTB1; KLF10; TCF4; SATB2; MYB; PIR; SPIB; TOB1; SATB1; KDM5D; SUV39H1