Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID16441 Linsitinib GSE70138 MCF10A Human 24h 3.33uM EID0006
Types Number Response transcription factors
Up-regulation 22 TSC22D3; CEBPD; HBP1; MAFF; FOXN3; SALL2; CRYM; ZBTB16; MYRF; IFI16; MAGED1; CUX2; RBPMS; SOX11; MXI1; TFEC; ARNT2; PBX1; ETV5; HOXC6; THAP11; FOS
Down-regulation 20 CCNE1; MED21; ELF4; RAN; ENO1; CRY1; CUX1; FOXC1; TLE4; SMAD6; SMAD7; TBL1X; NR2F2; ID4; TCF7; SATB2; TOX; LEF1; PEG3; SUV39H1