Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID16440	Linsitinib	GSE70138	MCF10A	Human	24h	10uM	EID0006

Response Information :

Types	Number	Response transcription factors
Up-regulation	68	JUP; CALCOCO1; ZNF589; PRDM2; PPARG; MYRF; NCOA3; ZNF423; ZNF117; EHF; NFATC4; SUPT6H; IRF9; ZFPM2; PBX1; OVOL2; TXNIP; CHD8; TSC22D3; ING4; INSR; SNAI2; ST18; BHLHE41; MEIS2; RCOR1; HOXD1; ARNT2; PCGF3; SALL2; MAFF; NPAS2; HIC2; DMTF1; IRF6; ZBTB16; FOXN3; NR1H3; TP63; TCF4; TCEA2; HDAC9; CUX2; ZMYND8; ZNF711; SOX9; TCF21; KLF11; KLF5; KLF7; DLX2; FOXF2; SOX13; MKL2; HHEX; PHIP; BTG1; FOXG1; VPS72; POU2AF1; ZHX2; TRIB3; FOXF1; MECOM; GATA6; SOX17; BASP1; TRIM29
Down-regulation	36	HOXA5; HOXA7; PURA; KLF2; ENO1; NR1D2; TMF1; ING3; EED; HNRNPD; DEK; HOXB7; CRY1; RBM14; NR4A2; EGR3; ID3; SMAD1; HMGB1; DNMT3B; ASCL1; NPM1; AFF1; IRX5; PTTG1; LEF1; CREB1; PSIP1; REPIN1; NCOA1; BHLHE40; PITX1; ID4; HOXC6; SATB1; SUV39H1